Beta1 integrins Definition The integrins are a family of cell membrane glycoproteins that function in cell-cell adhesion and two-way signaling. Integrins are composed of α and β subunits that span the cell membrane and have a large extracellular domain and a smaller cytoplasmic domain. They are...
Beta-1 integrins mediate substrate dependent effects of 1alpha,25(OH)2D3 on osteoblasts Surface micron-scale and submicron scale features increase osteoblast differentiation and enhance responses of osteoblasts to 1,25-dihydroxyvitamin D(3) [1... Z Schwartz,BF Bell,L Wang,... - 《Journal of ...
Blocking beta1 integrins dramatically reduced both the number of end buds per gland and the extent of the mammary ductal network, compared with controls. These effects were specific to the end buds since the rest of the gland architecture remained intact. Reduced development was still apparent ...
Downregulation of β1 Integrins by Ebola Virus Glycoprotein: Implication for Virus Entry (2000) Downregulation of beta1 integrins by Ebola virus glycoprotein: implication for virus entry. Virology 278: 20-26.Downregulation of β1 Integrins by ... Ayato Takada and Shinji Watanabe and Hiroshi Ito ...
1 reagents referenced in Distinct roles of the beta 1-class integrins at the developing and the mature hippocampal excitatory synapse.
Integrin-extracellular matrix interactions are important determinants of beta cell behaviours. The β1 integrin is a well-known regulator of beta cell
Moreover, it has been demonstrated that in the PDAC, hERG1 is coexpressed and interacts with different membrane receptors, such as EGFR and β1-integrins [17]. The molecular interaction between hERG1 and β1-integrins influences the channel activity. It is a gating-dependent complex formation ...
2007. Crucial role of fibroblast integrins alpha 2 and beta 1 in maintaining the structural and mechanical properties of the skin. J Dermatol Sci 45: ... T Fujimura,Y Takema,S Moriwaki,... 被引量: 0发表: 0年 Activation of the integrins alpha 5beta 1 and alpha v beta 3 and focal ad...
To study the functions of beta 1 integrins in the vessel wall, we used monoclonal antibody (MAb) 15/7, which recognizes an activation epitope of beta 1 integrin subunits, and MAb 8A2, which induces a high affinity form of beta 1 integrins recognized by MAb 15/7. Immunohistochemical analyses...
1 reagents referenced in Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains.