PROBLEM TO BE SOLVED: To obtain a new thermally stabler α-galactosidase protein derived from a strictly anaerobic thermophilic bacterium, and to provide a gene encoding the protein, a recombinant vector containing the gene, a transformant containing the recombinant vector, and to provide a method...
The first gene (named aga) codes for an enzyme with an alpha-galactosidase activity. The second gene (named galR) codes for a transcriptional regulator which would act as a regulator of aga. When present in a lactic acid bacterium such as , this DNA fragment can modify the sugar ...
Utilizing galactosidase gene with high specific activity and top liquid fermentation to keep product high activity High temperature-resistant Special post-process technic makes high activity at 85°C Function Decomposing α-galactosidase bond in animal feedstuff. Improving feed quality and utilization of en...
Genetic analysis of the alpha-galactosidase A gene was performed in 22 hemizygous males and 34 females. One of the female patients with severe disease phenotype showed homozygosity for the recurrent c.644A>G mutation due to parental consanguinity. The c.644A>G mutation that has previously been ...
Identification of a novel mutation in the alpha-galactosidase A gene in patients with Fabry diseasedoi:10.1016/j.clinbiochem.2012.03.015Fabry diseaseAlpha-galactosidase AHigh resolution meltingMutation c.614delCObjectives Mutation analysis of the alpha-galactosidase A (GLA) gene is a valuable tool ...
Gene ID (NCBI) 2717 RRID AB_2883263 Conjugate CoraLite® Plus 488 Fluorescent Dye Excitation/Emission Maxima Wavelengths 493 nm / 522 nm Form Liquid Purification Method Protein A purification UNIPROT ID P06280 Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. Storage...
Gene ID (NCBI) 2717 RRID AB_2881520 Conjugate Unconjugated Form Liquid Purification Method Protein A purification UNIPROT ID P06280 Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions Store at -20°C. Stable for one year after shipment. Aliquoting is unnecess...
The alpha-galactosidase A gene has been mapped to the region q22.1 of the X chromosome.5–8 When mutated, a progressive accumulation of a glycolipid called globotriaosylceramide (Gb3) affects mainly endothelial and vascular smooth muscle cells and causes damage to many major organs1 including ...
Fabry disease: six gene rearrangements and an exonic point mutation in the alpha-galactosidase gene. Fabry disease, an X-linked recessive disorder of glycosphingolipid catabolism, results from the deficient activity of the lysosomal hydrolase, alpha-galact... HS Bernstein,DF Bishop,KH Astrin,......
A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. 仅用于科研。不用于诊断过程。未经明确授权不得转售。