Zonisamide is used together with other medicines to treat partial seizures in adults and teenagers at least 16 years old.Zonisamide may also be used for purposes not listed in this medication guide.Zonisamide side effectsGet emergency medical help if you have signs of an allergic reaction (hives,...
Also found in: Wikipedia. zonisamide [zo-nis´ah-mīd″] a sulfonamide that acts as an anticonvulsant , used as an adjunct in the treatment of partial seizures in adults; administered orally. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition....
Uses and Administration Zonisamide, a benzisoxazole derivative, is used as an adjunctive antiepileptic in the treatment of partial sei- zures, with or without secondary generalisation. In the UK, the usual initial oral dose in adults over 18 years of age is 50 mg daily in 2 divided doses,...
However, the drug has been used in some pediatric patients† [off-label] for the treatment of epilepsy.Studies conducted with pediatric patients indicate that frequency of some adverse effects (e.g., metabolic acidosis, oligohidrosis and hyperthermia) may be increased compared with adults.Oligo...
Side effectsAbstarct Zonisamide (Zonegran, Excegran) is a new-generation, broad-spectrum antiepileptic drug (AED) currently approved as adjunctive therapy for the treatment of medically refractory partial seizures in adults in the US and as adjunctive therapy or monotherapy in the control of partial ...
Besides, it is approved to be applied as an adjunctive therapy in adults suffering from infantile spasm, mixed seizure types of Lennox–Gastaut syndrome, myoclonic, and generalized tonic clonic seizure. Recent studies have proved that zonisamide can acts as a migraine preventative medication and is...
In Japan, repeat administration of zonisamide at dosages of up to 13 mg/kg/day to children, and 18.6 mg/kg to adults, resulted in plasma concentrations linearly proportional to the dose given; however, when administered in a multiple dose regimen to patients in the US, zonisamide exhibited ...
Zonisamide for Weight Reduction in Obese Adults: A 1-Year Randomized Controlled Trial BACKGROUND: Obese individuals who have failed to achieve adequate weight loss with lifestyle changes have limited nonsurgical therapeutic options. We evalu... KM Gadde,MF Kopping,WH Nd,... - 《Archives of Inte...
Approximately 97 million adults in the United States are estimated to be overweight or obese, with a substantial increase of this epidemic in the recent years. With both conditions, there is a considerable increase in the prevalence of many comorbid illnesses including type 2 diabetes, coronary hea...
Moreover, normalization of sleep has been noted. Tolerability of the therapy is good. No side effects were noted.doi:10.17650/2073-8803-2015-1-47-63K. Yu. МukhinO. A. PylaevaRussian Journal of Child Neurology