Yes 相关蛋白 (YAP) 是 Hippo 信号通路中的关键转录因子。YAP 是一种以非活性形式存在于细胞质中的癌蛋白,当被激活时,它易位到细胞核并激活负责细胞分裂和凋亡的基因的转录。 参考文献 [1]. Abylkassov R, et al. Role of Yes-associated protein in cancer: An update. Oncol Lett. 2016 Oct;12(4)...
___转录共激活因子相关蛋白（YAP）是脊椎动物器官大小和增值的主要调节器。像这样，YAP可以在许多活性异常增加的组织类型中像癌细胞一样迅速增长。YAP 增强了对肿瘤进展和转移重要的多个过程，包括细胞增殖、转化、迁移和侵袭。The transcriptional coactivator Yes-associated protein(YAP)is a major regulator of organ...
Yes-associated protein (YAP) was identified based on its ability to associate with the SH3 domain of Yes. It also binds to other SH3 domain containing proteins such as Nck,Crk,Src,and Abl. YAP is a transcriptional coactivator. It interacts with 13-3
ChemicalBook 致力于为化学行业用户提供YAP (Yes-associated Protein, YAP65)的性质、化学式、分子式、比重、密度,同时也包括YAP (Yes-associated Protein, YAP65)的沸点、熔点、MSDS、用途、作用、毒性、价格、生产厂家、用途、上游原料、下游产品等信息。
YAP (Yes-associated Protein, YAP65) 中文名: 中文别名: CBNumber: CB2979115 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商1 YAP (Yes-associated Protein, YAP65)化学性质 安全信息 YAP (Yes-associated Protein, YAP65)性质、用途与生产工艺 ...
I 型子宫内膜癌组织 Amot,YAP1 蛋白表达与临床病理参数 和预后的关系研究 angiomotin (Amot) and Yes-associated protein 1 (YAP1) expression and clinicopathological parameters and prognosis in type I endometrial cancer (EC) tissues... 王俊毅,陆晓媛,经莉,... - 《Progress in Modern Biomedicine》 被引...
Yes-associated Protein (YAP) and its paralog Transcriptional Coactivator with PDZ-binding Motif (TAZ) are major regulators of gene transcription/expression, ... M Kofler,A Kapus - 《Cancers》 被引量: 0发表: 2023年 Lipophilic Statins Inhibit YAP Nuclear Localization, Coactivator Activity, and Migra...
Yes-associated protein (YAP), a key effector of the Hippo signaling pathway, is persistently activated in diabetic hearts, and YAP plays an essential role in mediating the exacerbation of heart failure in response to pressure overload in the hearts of mice fed a high-fat diet. YAP induced ...
C Manson-Bishop5, P Smith6, SA Danovi1, O Pardo2, T Crook6, CA Mein5, NR Lemoine4, LJ Jones3 and S Basu*,1 Yes-associated protein (YAP) has been shown to positively regulate p53 family members and to be negatively regulated by the AKT proto-oncogene product in promoting apoptosis...
we uncover a critical and hitherto unappreciated role for Yes-associated protein (YAP), an evolutionarily conserved transcriptional coactivator with potent oncogenic potential. We show that YAP is highly expressed and nuclear in single-layered basal epidermal progenitors. Notably, nuclear YAP progressively...