2011 . The XAF1 tumor suppressor induces autophagic cell death via upregulation of Beclin-1 and inhibition of Akt pathway . Cancer Lett 310 : 170 – 180 .Sun PH, Zhu LM, Qiao MM, et al. The XAF1 tumor suppressor induces autophagic cell death via upregulation of Beclin-1 and inhibition...
Sun, P. H. et al. The XAF1 tumor suppressor induces autophagic cell death via upregulation of Beclin-1 and inhibition of Akt pathway., 170–180 (2011). Zhu, L. M. et al. Tumor suppressor XAF1 induces apoptosis, inhibits angiogenesis and inhibits tumor growth in hepatocellular carcinoma.,...
The XAF1 tumor suppressor induces autophagic cell death via upregulation of Beclin-1 and inhibition of Akt pathway Autophagy is designated as type II programmed cell death and may confer a tumor-suppressive function. Our previous studies have shown that XIAP-associated ... Ping Hu Sun and Li ...
2001, Journal of Biological Chemistry Show abstract Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy 2003, Leukemia The role of zinc in caspase activation and apoptotic cell death 2001, BioMetalsView...
首先介绍一下 FGFR,它的全称是Fibroblast Growth Factor Receptor,其自身作用机制是作为酪氨酸激酶家族的一员,参与细胞增殖,分化,迁移和生存。当 FGFR 发生过表达时,FGFR 信号通路被激活,会导致正常细胞发生癌变,其中RAS-RAF-MAPK,SATAHE PI3K-AKT是...
目的:研究阿托伐他汀是否能够通过激活磷脂酰肌醇-3-激酶 (PI3K)/Akt 通路和线粒体 ATP 敏感性钾来增强连接蛋白 43 (Cx43) 的表达,从而防止心肌缺血再灌注损伤。 方法:在离体大鼠心脏灌流前降支(LAD)缺血30 min后,分别给予经典...
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forked fromHashnode/starter-kit NotificationsYou must be signed in to change notification settings Fork0 Star0 Files 83092c3 packages .gitignore README.md package.json pnpm-lock.yaml pnpm-workspace.yaml Latest commit panda-sandeep Update sanitize-html dep ...
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