Developmental biology WNT/beta-catenin signaling regulates multiple aspects of lateral line morphogenesis THE UNIVERSITY OF UTAH Tatjana Piotrowski AmanAndrewDuring development, groups of cells in the embryo must organize into precise morphologies required for the function of tissues and organs to enable ...
Here, we review the regulation of Wnt/beta-catenin signaling in glioma, with particular focus on the expression signatures of the main components in Wnt/beta-catenin signaling, the role of key factors in Wnt/beta-catenin signaling, and crosstalk with other signaling pathways. Finally, we discuss...
Fig. 1: Inhibition of the Wnt/beta-catenin signaling enhances GC cells’ sensitivity to ferroptosis. Full size image TCF4 acts as a repressor of ferroptosis in GC cells Fig. 2: TCF4 acts as a repressor of ferroptosis in GC cells.
Wnt/beta-catenin signaling in development and disease. A remarkable interdisciplinary effort has unraveled the WNT (Wingless and INT-1) signal transduction cascade over the last two decades. Wnt genes encode sm... H Clevers - 《Cell》 被引量: 8997发表: 2006年 WNT/beta-catenin signaling in ...
Wnt/beta-catenin signaling in development and disease. A remarkable interdisciplinary effort has unraveled the WNT (Wingless and INT-1) signal transduction cascade over the last two decades. Wnt genes encode sm... H Clevers - 《Cell》 被引量: 8992发表: 2006年 Wnt/beta-catenin signaling: ...
The Wnt/Wingless signaling transduction pathway plays an important role in both embryonic development and tumorigenesis. beta-Catenin, a key component of the Wnt signaling pathway, interacts with the TCF/LEF family of transcription factors and activates
7, No. 15CWP232228 targets liver cancer stem cells through Wnt/β‑catenin signaling: a novel therapeutic approach for liver cancer treatmentJi‑Young Kim 1,2,* , Hwa‑Yong Lee 3,* , Kwan‑Kyu Park 4 , Yang‑Kyu Choi 2 , Jeong‑Seok Nam 5 , In‑Sun Hong 6,71 Center ...
The Wnt-beta-catenin signaling pathway is involved in cell proliferation, differentiation and morphogenesis. Recently, mutations of the low-density lipoprotein receptor-related protein 5 (LRP5 ) gene, a receptor of this signaling, have been described to be associated with both osteoporosis-pseudoglioma...
Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Stem cells are defined by their intrinsic capacity to self-renew and differentiate. Cancer stem cells retain both these features but have lost homeostatic ... R Fodde,T Brabletz - 《Current Opinion in Cell Biology》 被引量...
深入研究「MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway」主題。共同形成了獨特的指紋。 Signal Transduction Biochemistry, Genetics and Molecular Biology 100% Cancer Cell Biochemistry, Genetics and Molecular...