Major factors that may contribute to the proliferation of the leiomyoma are the decrease in the protein CCN5 and the expression of the gene HBP1--both of which are components of the Wnt signaling pathway, a fundamental pathway in normal development and in disease. CCN5 is a matricelluar ...
Capsaicin inhibits the Wnt/β-catenin signaling pathway by down-regulating PP2A Dong-Seok Park,Gang-Ho Yoon,Hyun-Shik Lee,Sun-Cheol Choi.Capsaicin inhibits the Wnt/β-catenin signaling pathway by down-regulating PP2A[J].Biochemical ... Dong-Seok.Park,Gang-Ho.Yoon,Hyun-Shik.Lee,... - 《Bio...
The miR-199b-3p/CCDC88A axis regulates the OS cell malignant behaviors via the Wnt/β-catenin pathway and the EMT process in vitro. (A) Inhibition of the expression of miR-199b-3p activates the Wnt/β-catenin signaling pathway and the epithelial–mesenchymal transition process. (B) The miR...
The Wnt/β-catenin signaling pathway is a central event in CRC, which promotes cancer progression by driving tumor cell proliferation, migration and invasion, and has potential value as a therapeutic target in the treatment of CRC. The mRNA expression of cyclin D1, met, c-myc and MMP7 were...
3.3.Eif2s3yactivates Wnt/β-catenin signaling pathway in SSCs To evaluate the proliferation mechanism ofEif2s3y, we investigated the signaling pathways of the proliferation-related through western blotting in WT and Transgenic-Eif2s3ymicetestes tissue. MEK-ERK signal can directly and indirectly par...
Wnt/β-catenin signaling mediates the antitumor activity of magnolol in colorectal cancer cells. Abnormal activation of the canonical Wnt/-catenin pathway and up-regulation of the -catenin/T-cell factor (TCF) response to transcriptional signaling play ... YJ Kang,HJ Park,HJ Chung,... - 《Mole...
miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/β-catenin signaling pathway miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/beta-catenin signaling pathway. Oncology Reports 2015;34(1... L Song,L ...
There is no evidence that WT1 does regulate the Wnt-4/beta-catenin-independent pathway which is activated in the Pit-1-expressing subset of pituitary adenomas. 展开 关键词: WT1 adenohypophysis pituitary adenoma oncogene DOI: 10.1007/s12022-009-9078-y ...
In conclusion, PRRSV infection activates the Wnt/beta-catenin signaling pathway via Nsps 1 alpha, 1 beta, 3, 4, 7, 10, and 12, and proteins encoded by ORFs 2b, 3, and 5. The Wnt/beta-catenin pathway then inhibits PRRSV replication by enhancing the NF-kappa B-dependent innate immune ...
Aberrant activation of the WNT/beta-catenin signaling pathway has been implicated in the molecular pathogenesis of EADC. The caudal-related homologues, CDX1 and CDX2, are two target genes of the WNT pathway and they are suggested to be the primary molecular determinants of Barrett metaplasia. ...