that many presumed intrachromosomaltrans-meQTLs are not truetrans-meQTLs but instead long-rangecis-meQTLs. We, therefore, excluded long-rangecis-meQTLs (i.e., SNPs > 1 Mb but within 5 Mb of CpGs), leaving 630 thousandtrans-meQTL SNPs (for 10.6 thousand CpGs, 1.6 million pairs...
These novel associations suggest a wide range of transport functions for SLC23A3. Among the novel association signals at index variants enriched in Finns, we identified an association with 3-amino-2-piperidone at the putatively-deleteriousOAT missense variant p.Leu402Pro (rs121965043, β =...
In patients with no outcome events, EF, left ventricular end systolic/diastolic volume indices (LVEDVi, LVESVi), left atrial volume index (LAVi), mitral E/e′ ratio and pulmonary artery systolic pressure (PASP) significantly improved during 6 months post treatment initiation, in contrast to ...
For Criterion 2, the SD of the averaged BP differences between the test device and reference BP per individual (N = 85) was 5.15/5.81 mmHg (systolic/diastolic; threshold < = 6.88/6.95 mmHg).#The Braun BUA4000 automated oscillometric home BP monitor fulfilled all the requirements of the ...
The molecular factors which control circulating levels of inflammatory proteins are not well understood. Furthermore, association studies between molecular probes and human traits are often performed by linear model-based methods which may fail to accoun
Systolic and diastolic blood pressure decreased significantly. Meaning The findings suggest that this population-based intervention was associated with lower urinary sodium excretion and blood pressure in a large population in China. Abstract Importance High salt intake is associated with hypertension, which...
In NEST, methylation differences at CpG sites of the TAPBP gene were associated with BMI z-score (cg23922433 and cg17621507) and systolic BP percentile (cg06230948) in female and systolic (cg06230948) and diastolic (cg03780271) BP percentile in male offspring. Together, these findings suggest ...
Systolic and diastolic blood pressure decreased significantly. Meaning The findings suggest that this population-based intervention was associated with lower urinary sodium excretion and blood pressure in a large population in China. Abstract Importance High salt intake is associated with hypertension, which...
J. Goldberg, "Risk factors and comorbidities in a community-wide sample of patients hospitalized with acute systolic or diastolic heart failure: The worcester heart failure study," Coron Artery Dis., vol. 21, pp. 137-43, 2010.Chinali M, Joffe SW, Aurigemma GP, Makam R, Meyer TE, ...
colocalization techniques and scRNA-seq or snRNA-seq data, and the generation and testing of a TAAD PRS. This figure was created with the assistance of BioRender. Abbreviations: LDL-C, LDL cholesterol; HDL-C, HDL cholesterol; TG, triglycerides; SBP, systolic blood pressure; DBP, diastolic ...