Energy deficit in Huntington disease: why it matters Huntington disease (HD) is an autosomal dominant neurodegenerative disease with complete penetrance. Although the understanding of the cellular mechanisms ... F Mochel,RG Haller - 《Journal of Clinical Investigation》 被引量: 279发表: 2011年 ...
Could the mutation that causes Huntington's disease actually be making people healthier in their younger years? That's the theory being proposed to explain why the Huntington's disease (HD) gene is increasing in the population - despite eventually rendering many of its carriers unable to control...
Huntington's disease is caused by a single dominant allele and results in progressive mental and neurological damage. The disease usually becomes symptomatic when a person is between 30 and 50 years old and the patient usually dies within 15 years of diagnosis. Approximately 1 in 25,000 Caucasian...
Millions of people across America (not to mention worldwide) struggle with stubborn abdominal fat, which can be difficult to shed even when a healthy lifestyle is adopted. Not only is abdominal fat, also called visceral fat or ‘belly fat,’ unsightly, it can lead to an increased risk of...
1.Disinfectant Properties:One of the primary reasons Lugol's iodine is applied topically is its potent disinfectant capabilities. It can be applied to minor wounds, cuts, and abrasions to prevent infections. 2.Treatment of Skin Conditions:Beyond its disinfectant properties, Lugol's iodine has been...
Creighton, S., Almqvist, E., MacGregor, D., Fernandez, B., Hogg, H., Beis, J., et al. (2003). Predictive, pre-natal and diagnostic genetic testing for Huntington’s disease: the experience in Canada from 1987 to 2000. Clinical Genetics, 63(6), 462–475. Article CAS Google Scho...
Why is late-onset Huntington disease under-diagnosed?Huntington disease is still under-diagnosed by neurologists and psychiatrists -particularly in the elderly population. Dr Teodorczuk explores the reasons for under-diagnosis and misdiagnosis and provides an update on the features of Huntington disease ...
Likewise, well-controlled intervention studies are often impractical in the setting of established neurodegenerative disease. It is this that makes understanding sleep and circadian abnormalities in Huntington's disease (HD) important: as a monogenic fully penetrant neurodegenerative condition presenting in ...
Presents a letter to the editor in response to an article on using minocycline in treating Huntington's disease, by Denovan-Wright et al. in a 2003 issue of the "Journal of Psychopharmacology."BonelliUniversity Clinic of PsychiatryRaphael M....
A standard of care for Huntington's disease: who, what and why. Neurodegen Dis Manage. 2012; 2 :1–5.Simpson, S. A., & Rae, D. (2012). A standard of care for Huntington's disease: who, what and why. Neurodegenerative Disease Management, 2, 1-5....