Apart from CYP3A4, grapefruit components can also block CYP1A2, CYP2A6, CYP2C9, CYP2C19, and CYP2D6 [14]. Scientists think that grapefruit also likely blocks CYP3A5 with the same intensity as CYP3A4 (these enzymes have highly similar functions), but this hasn’t been properly studied [...
Why Shouldn't You Take Medicine with Grapefruit Juice? What are the side effects of grapefruit? Grapefruit juiceinhibits a chemical in the intestine needed to break down many drugsin the body. The absence of this chemical can lead to higher blood levels. In effect, the drug becomes more ...