Next-generation sequencing is advancing the detection, characterization, and surveillance of drug-resistant tuberculosis strains.
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has rapidly progressed from a research tool to a clinical application for the diagnosis and management of tuberculosis and in public health surveillance. This development has been facilitated by drastic drops in cost, advances in technology and...
The fight against tuberculosis is getting smarter with whole genome sequencing (WGS). In a non-commercial trial ( Lancet Respir Med doi:10.1016/S2213-2600(15)00466-X) WGS was 93% accurate at first attempt. Diagnosis took nine days—three weeks faster than conventional diagnostics for ...
The Philippines has a high incidence of tuberculosis disease (TB), with an increasing prevalence of multidrug-resistant(MDR-TB) strains making its control difficult. Although the."Manila" ancient lineage 1 strain-type is thought to be prevalent in the country, with evidence of export to others,...
摘要: Whole genome sequencing (WGS) has the potential to 关键词: Mycobacterium tuberculosis Phylogenetic analysis Online tools Rapid susceptibility testing Whole genome sequencing 被引量: 2 年份: 2017 收藏 引用 批量引用 报错 分享 求助全文 通过文献互助平台发起求助,成功后即可免费获取论文全文。 请先...
3. Challenges associated with current drug-resistant tuberculosis diagnostics 4. Role of whole genome sequencing in drug-resistant tuberculosis management 5. Limitations and challenges to implementation of whole genome sequencing for drug-resistant tuberculosis management 6. Framework for implementation of who...
1 Rapid Whole Genome Sequencing of M. tuberculosis directly from 2 clinical samples33 The rapid identification of antimicrobial resistance is essential for ... AC Brown,JM Bryant,K Einer-Jensen,... 被引量: 0发表: 0年 Whole-genome sequencing for rapid susceptibility testing of M. tuberculosis....
Decision letter | Large-scale whole genome sequencing of M. tuberculosis provides insights into transmission in a high prevalence area QA Karim - 《Elife》 被引量: 36发表: 2015年 Sequencing of the pncA Gene in Members of the Mycobacterium tuberculosis Complex Has Important Diagnostic Applications: ...
The emergence of whole genome sequencing (WGS) technologies as primary research tools has allowed for the detection of genetic diversity in Mycobacterium tuberculosis (Mtb) with unprecedented resolution. WGS has been used to address a broad range of topics, including the dynamics of evolution, transmi...
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