2024年5月17日世界卫生组织发布了最新的“细菌重点病原体清单”(WHO bacterial pathogen priority list,WHO BPPL),这份名单包含了15类抗菌药物耐药(antibiotic resistant,ABR)病原体。2024年WHO BPPL在2017年版本的基础上,更新并完善了抗菌药物耐药性病原体的优先顺序,将其分为严重级别组、高级别组和中级别组三个...
根据更新2024年世卫组织发布的细菌优先病原体清单(Bacterial Pathogen Priority List,BPPL),本文首先评估了目前抗菌药物研发、生产系统在多大程度上解决了重要耐药细菌病原体(drug-resistant bacterial priority pathogens, BPPs)引起的感染,并以此回顾了当前的研发情况,同时引导后续的研发应面向最迫切但尚未满足的医疗需求。
[2]Chiurlo M, Mastrangelo A, Ripa M, Scarpellini P. Invasive fungal infections in patients with COVID-19: a review on pathogenesis, epidemiology, clinical features, treatment, and outcomes. New Microbiol. 2021;44(2):71...
根据更新2024年世卫组织发布的细菌优先病原体清单(Bacterial Pathogen Priority List,BPPL),本文首先评估了目前抗菌药物研发、生产系统在多大程度上解决了重要耐药细菌病原体(drug-resistant bacterial priority pathogens, BPPs)引起的感染,并以此回顾了当前的研发情况,同时引导后续的研发应面向最迫切但尚未满足的医疗需求。
[3] WHO fungal priority pathogens list to guide research, development, and public health action [4] Bongomin F, Gago S, Oladele RO, Denning DW. Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision. J Fungi (Basel). 2017;3(4):57. Published 2017 Oct 18. ...
Some new fungal species are believed to have emerged due to climate change. For example,Candida auris, which is in the WHO critical priority group, is a new fungal pathogen that has emerged since 2009 and has now spread globally, with reports of infections from every continent [14].Candida ...
The World Health Organization (WHO) has released a fungal priority pathogen list (FPPL) to prioritize fungal pathogens based on their research and development needs and public health importance. The list categorizes 19 major invasive fungal pathogens into critical, high, and medium priority, ...
[3]WHO fungal priority pathogens list to guide research, development, and public health action [4]Bongomin F, Gago S, Oladele RO, Denning DW. Global and Multi-National Prevalence of Fungal Diseases-Estimate Precision. J Fungi (Basel). 2017;3(4):57. Published 2017 Oct 18. ...
•WHOBacterialPriorityPathogensList,2024:bacterial datacollectionandsharing,andimplement pathogensofpublichealthimportancetoguide investmentstrategiesthatarefocusedonresearch,developmentandstrategiestopreventand addressingtheneedsofvulnerablepatients,controlantimicrobialresistance.Geneva:WorldHealth ...
Table 1 World Health Organisation (WHO) Pathogen Priority List (PPL) organisms isolated in the study site by specimen type from January 2014 to October 2019. Full size table Among the main WHO PPL organisms identified, 72% ofE. coliand 63% ofKlebsiellaspp. were resistant to 3rd generation ...