DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis. Lancet Oncol. 18, 682–694 (2017). Article CAS PubMed Google Scholar Choudhury, A. et al. Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities. Nat. ...
The Simpson grading scale for the classification of the extent of meningioma resection provided a tremendous movement forward in 1957 suggesting increasing the extent of resection improves recurrence rates. However, equal, if not greater, movements forward have been made in the neurosurgical community ...
Williams EA, Wakimoto H, Shankar GM, Barker FG 2nd, Brastianos PK, Santagata S, Sokol ES, Pavlick DC, Shah N, Reddy A, Venstrom JM, Alexander BM, Ross JS, Cahill DP, Ramkissoon SH, Juratli TA. Frequent inactivating mutations of the PBAF complex gene PBRM1 in meningioma with papillary...
Before discussing specific tumors, it is worth mentioning a few general changes in grading. The first is that WHO grades, which were previously listed in Roman numerals, are now listed in Arabic numerals. In addition, grading is now done within tumor types as part of the integrated diagnosis,...
The new 2021 WHO classification of CNS tumours has further integrated molecular data into the typing, subtyping and grading of major tumour groups. Such integration especially affects the classification of adult-type and paediatric-type diffuse gliomas, circumscribed astrocytic gliomas, ependymomas, embryo...
【摘要】 2021年世界卫生组织中枢神经系统肿瘤分类(第五版,简称新版肿瘤分类)在组织学诊断的基础上引入一系列分子诊断指标,形成整合诊断及分层报告体系,并新定义多种肿瘤类型和亚型,反映出目前神经肿瘤相关领域对此类疾病遗传背景和临床特征的理解。本文综述新版肿...
Any sample classified as one of the above-mentioned tumors in a lung biopsy warrants intense clinical review for an occult primary at more common sites, before assigning as a primary pulmonary tumor, even in the context of benign looking cytology (e.g., benign metastasizing meningioma), but ...
Sleep quality, sleep EEG pattern, mental well-being and cortisol secretion in patients with ruptured aneurysm post-treatment: a comparison with post-surgery meningioma patients and controls. Neuropsychobiology. 2016;73(3):148–59. https://doi.org/10.1159/000444492. Article CAS PubMed Google ...
Simpson grading of resection has been used as a predictor of intracranial meningioma (IM) recurrence. Histopathological findings, like the Ki-67/MIB-1 labeling index, may be useful in the assessment risk of recurrence. Our objective was to analyze the predictive value of meningioma recurrence ...
The role of adjuvant radiotherapy after gross total resection (GTR) of WHO grade 2 meningioma remains unclear, and conflicting results have been published.