最近笔者读了一篇题为"Controversies in the recent (2016) World Health Organization classification of acute myeloid leukemia"的文章。 文章阐述了世界卫生组织(WHO)分类中一些值得探讨的问题,不管是知识的更新,还是学习用于工作上指导骨髓形态学诊断都有一定意义。 01 原始细胞20%界值的争论 WHO采用20%原始细胞界...
今天读了"Controversies in the recent (2016) World Health Organization classification of acute myeloid leukemia",文章阐述了WHO分类中一些值得探讨的问题,不管是知识的更新,还是学习用于工作上指导骨髓形态学诊断都一定的意义。故整理了部分内容记录下来并分享,可能有理解不足的地方。 ...
ClassificationIn 2016 a revision of the World Health Organization (WHO) classification of acute myeloid leukemia (AML) was introduced that included changes to several disease categories. The WHO approach results in disease categories that are defined by a combination of clinical, morphologic, immuno...
There are 2 staging systems that are commonly used during diagnosis of acute myeloid leukemia (AML). The French-American-British (FAB) classification system is based on morphology to define specific immunotypes.
Since 1976 the classification of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) have followed the FAB classification. Several parameters from methods like multi-parameter immunophenotyping, cytogenetics and molecular genetics add informative informations over the last 25 years for ...
本研究以骨髓增生异常综合征(myelodysplastic syndrome/neoplasms,MDS)和急性髓细胞白血病(acute myeloid leukemia,AML)为例,重点介绍这两种重要的髓系肿瘤的诊断要点、重要概念,以及它们在WHO-HAEM5 和ICC分类发生的主要变化和不同,以便我们更...
The diagnosis is standardized, also the therapeutic and prognostic biomarkers are emphisezed during subtype classification. Here, it focus on the acute myeloid leukemia related part, discussing the changes in this updated review in comparison to the previous version and giving some views. Key words...
[9]Rudelius, Martina et al. “The International Consensus Classification (ICC) of hematologic neoplasms with germline predisposition, pediatric myelodysplastic syndrome, and juvenile myelomonocytic leukemia.” Virchows Archiv : an international journal of pathology vol. 482,1 (2023): 113-130. doi:10.10...
[1] Arber DA,Orazi A,Hasserjian R,et al.The 2016re-vision to theWorld Health Organization (WHO)classification of myeloid neoplasms and acuteleukemia [J].Blood,2016,127:2391-2405. [2] West AH,Godley LA,Churpek JE.Familial myelo-dysplasticsyndrome/acute leukemia syndromes:a re-view and utili...
Per the International Classification of Diseases (ICD), now in its 11th revision, each disease and disorder should be classified via specific codes published via the World Health Organization. AML is a disease that's classified, and this refers to acute myeloid leukemia....