Certain diseasesaffect only specific cells within the brain. For example, the symptoms ofmultiple sclerosisare caused by damage to the glial cells that manufacture and maintain the myelin sheath that insulates axons. Without this normal nerve covering, electrical transmission is compromised and symptoms...
providing the early support for the hypothesis of direct entry of SARS-CoV-2 into the brain via the olfactory and oral mucosa. Although loss of smell is a common symptom in COVID-19 patients, its manifestation likely depends on the genetic variability of the virus and its...
Patient-reported outcomes have been used in clinical trials to capture what matters most according to the daily life experience of people living with dementia (PLWD). Traditionally, the validity of self-reported hearing disability measures has been assessed using their correlations with the pure-tone...