The holy grail of pandemic preparedness is being able to predict how a virus will evolve just by looking at its genetic sequence. Those days are still a way off, but a growing number of research groups are using artificial intelligence (AI) to predict the evolution of SARS-CoV-2, influenza...
Multiple myeloma (MM) is the most common form of plasma cell malignancy, accounting for about 1.7% of all malignant tumors [1]. Although the use of a variety of treatment options such as high-dose chemotherapy, hematopoietic stem cell transplantation (HSCT), proteasome inhibitors (PIs), immunom...
but even the most intensive lifestyle interventions result in up to 10% mean weight loss (WL) and weight maintenance remains a challenge, as 80% of WL is expected to be regained over the next 5 years [4,5]. The main drivers for weight regain...
The worldwide prevalence of Parkinson’s disease (PD) has been constantly increasing in the last decades. With rising life expectancy, a longer diseas
What is the Reason That the Pharmacological Future of Chemotherapeutics in the Treatment of Lung Cancer Could Be Most Closely Related to Nanostructures? Platinum Drugs in Therapy of Non-Small and Small Cell Lung Cancer and Their Unexpected, Possible Interactions. The Review Kamil Szupryczyński, ...
Natalizumab (Tysabri) was the first monoclonal antibody approved for the treatment of relapsing forms of multiple sclerosis (MS). After its initial
In a lot of cases, the “normal” lab results do not reflect what is actually happening within the body. For example, in the case of subclinical hypothyroidism, while T4 and T3 thyroid hormone levels may be within normal ranges, thyroid antibody levels may be elevated. Antibodies can be ele...
It is not known when considering local and systemic inflammation/immune system activation, which one has greater importance in NAFLD and IBS pathogenesis. Also, the nervous system is implicated. In fact, inflammation participates in the development of mood disorders, such as anxiety and depression, ...
For patients with cancer, treatment may include combination therapy, including surgery and immunotherapy. Here, we review perioperative considerations for
Therefore, the study of CAF markers is of great importance for achieving breakthroughs in precision targeted therapy. In recent years, with the emphasis on tumor immune microenvironment and the development of molecular techniques, such as single-cell sequencing, there has been a great progress in ...