什么是质谱法（What is Mass Spectrometry）？质谱法是一种用于化学鉴定的分析技术。通过对感兴趣的样品进行电离和碎裂，并测量所形成的产物的质量电荷比，可以看到一个 "化学指纹"，从而帮助找出化学结构。质谱法也可用于识别未知化合物。质谱法与各种样品类型兼容，从气态样品到大型蛋白质。为了处理复杂环境中的样品，...
Spectrometry, MassManager, FacilityBuilding, AstburyScripps-Center. What is mass spectrometry? http:// masspec.scripps.edu/mshistory/whatisms_toc.php (Accessed 6 December 2010).American Society for Mass Spectrometry. (1998). What is mass spectrometry? (3rd ed.) Santa Fe, NM: American Society ...
How does mass spectrometry work? In MS analysis, the mass-to-charge ratio of ions is measured. This is done by ionizing a sample, separating the ions or fragments according to their mass-to-charge (m/e) ratio, and then detecting these charged particles by a detector/analyzer where molecula...
in the ionization process [represented M+H+ or M-H- if formed by the loss of a proton] or if the ion is formed by loss of an electron it is represented as the radical cation [M+.]. The accuracy of a mass spectrometer or how well it can measure the actual true mass...
Let us assume an analytical technique which involves the identification of the chemical substances by sorting gaseous ions in the electrical and magnetic field according to their mass to charge ratios. Such a technique is said to be mass spectrometry....
In many cases, the ions encountered in mass spectrometry have just one charge (z=1) so the m/z value is numerically equal to the molecular (ionic) mass in Da. Mass spectrometrists often speak loosely of the "mass of an ion" when they really mean the m/z ratio, but this convenient...
Mass spectrometry is a substance from a crime scene that is analyzed by a mass spectrometer in order to find the molecular makeup. Explore how mass spectrometry can be used to identify all kinds of evidence such as cloths, glass, dyes, metals, and even human tissue. ...
Mass Spectrometry-based Proteomics: What is it expecting ahead?IntroductionProtein Identification through Mass-Based Spectrometry Techniques and Peptide Mass FingerprintClassic In-Gel Protein Sample Treatment for Protein Identification through Peptide Mass FingerprintUltrasonic Energy for the Acceleration of In-...
“snips”) are single base-pair changes in DNA that occur at specific places in the genome. For example, most individuals carry the C nucleotide at a specific base position in the genome, but in a minority of individuals this is replac...
Consequently, the molecular mass of a protein is not a single value but a distribution of values, the isotopic distribution, represented by the spectral peaks of the monoisotopic ion (M) and a series of peaks (M + 1n, M + 2n, M + 3n…) differing from each other in the...