Long-term potentiation (LTP) is operationally defined as a long-lasting increase in synaptic efficacy following high-frequency stimulation of afferent fibers. Since the first full description of the phenomenon in 1973, exploration of the mechanisms underlying LTP induction has been one of the most ac...
Dolphin (1982) What is the mechanism of long-term potentiation in the hippocampus? Trends Neurosci. 5: 289-290.Bliss, T. V. P., Dolphin, A. C. (1982) What is the mechanism of long-term potentiation in the hippocampus?. Trends Neurosci. 5: pp. 289-290...
If this occurs often, a secure neural network is set up, as if imprinted, allowing the brain to reliably access the information eventually. Hence, a discrete act of learning has been initiated, reinforced, and embedded, a process referred to as Long-Term Potentiation (LTP). A person experien...
LTP has be... MT Rogan,UV Stäubli,JE Ledoux - 《Nature》 被引量: 2292发表: 1997年 Fear conditioning and long-term potentiation in the amygdala: what really is the connection? (2008). Fear conditioning and long-term potentiation in the amygdala: what really is the connection? Ann. N....
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examined. Our results demonstrated that NPD1 is a highly potent endogenous inhibitor of TRPV1 (IC50_0.4 nM). NPD1 blocked both TRPV1 and TNF-_-mediated spinal cord synaptic transmission and long-term potentiation (LTP). In addition, spinal adm NPD1的角色在调控突触神经的传输和痛苦有被审查...
Abolition of long-term stability of new hippocampal place cell maps by NMDA receptor blockade Science, 280 (1998), pp. 2121-2126 View in ScopusGoogle Scholar 116 R.D. Blitzer, et al. Cholinergic stimulation enhances long-term potentiation in the CA1 region of rat hippocampus Neurosci. Lett....
The discovery of activity-induced long-term potentiation (LTP) and long-term depression (LTD) of central synapses in the 1970s and 80s further sparked the interest of a whole generation of neurobiologists in studying synaptic plasticity and its relationship to memory. There is now general ...
The discovery of activity-induced long-term potentiation (LTP) and long-term depression (LTD) of central synapses in the 1970s and 80s further sparked the interest of a whole generation of neurobiologists in studying synaptic plasticity and its relationship to memory. There is now general ...
Since glutamate activates both ionic and G-protein coupled receptors, which are responsible for a lasting increase in efficacy of synaptic transmission in the spinal cord [61] and in the brain [62] (i.e., long term potentiation (LTP)), the hypothesis was advanced that tsDCS might be used...