It is known that type 2 diabetes causes damage to the brain and body relative to sugar and the insulin response. Mild cognitive dysfunction can also be a result of type 2 diabetes. Is this a path to Alzheimer's disease? Dr. Sam Gandy, M.D., Ph.D., said on the Alzheimer’s Associa...
AfterAlzheimer's disease, Parkinson's disease is the second-most common neurodegenerative disorder in the country, the NIH notes. Is Parkinson's genetic? The cause of Parkinson's is unknown but scientists believe several factors play a role, including genetics, environmental triggers and other heal...
disintegration of intracellular junctions, and increased permeability of the BBB. Invasion of T-lymphocytes and macrophages via the BBB activates microglia and astrocytes leading to cerebral cytokine, chemokine, and nitric oxide release, which causes neuronal...
Viral S protein accumulates in the host cell endoplasmic reticulum (ER) and directly modulates the host unfolded protein response (UPR) to promote viral replication [13]. After entering the host cell, the COVID-19 virus genome is then released inside the host cell and the virus replicates its...
physiopathology of numerous cell types. In neural cells the nuclear lipids are involved in cell proliferation, differentiation, inflammation, migration and apoptosis. Abnormal metabolism of nuclear lipids might be closely associated with tumorigenesis and neurodegenerative diseases such as Alzheimer disease ...