1. Warburg, O.; Posener, K.; Negelein, E., On the metabolism of carcinoma cells.BiochemZ1924,152, 309-344. 2. Warburg, O.; Wind, F.; Negelein, E., The metabolism of tumors in the body.J Gen Physiol1927...
1. Warburg, O.; Posener, K.; Negelein, E., On the metabolism of carcinoma cells. Biochem Z 1924, 152, 309-344. 2. Warburg, O.; Wind, F.; Negelein, E., The metabolism of tumors in the body. J Gen Physiol 1927, 8 (6), 519-530. 3. Warburg, O., On the origin of canc...
It has been about nine decades since the proposal of Otto Warburg on the metabolism of cancer cells. Unlike normal cells which undergo glycolysis and oxidative phosphorylation in the presence of oxygen, proliferating and cancer cells exhibit an increased uptake of glucose and increased rate of glycol...
Warburg O, Posener K, Negelein E. On the metabolism of carcinoma cells. Biochem Z , 1924 , 152: 309 -44 Google Scholar [2] Warburg O, Wind F, Negelein E. The metabolism of tumors in the body. J Gen Physiol , 1927 , 8: 519 -30 Google Scholar [3] Liberti MV, ...
Compared to normal cells, cancer cells have a unique metabolism by performing lactic acid fermentation in the presence of oxygen, also known as the Warburg... W Zhou,LA Liotta,EF Petricoin - 《Cancer Genomics & Proteomics》 被引量: 7发表: 2017年 The unveiling of the Warburg effect and the...
The Warburg Effect The ability of cancer cells to use anaerobic metabolism and to generate lactate, even in the presence of adequate oxygen, is known as the Warburg effect (Warburg et al., 1924; Warburg, 1954). Lactate added to cultured fibroblasts increases their HA production (Stern et al...
of normal cells. These differences are readily apparent at the level of the basal metabolism involved in energy and biomass production [1]. In normal cells, glucose is taken up by specific transporters (GLUTs—glucose transporters) and subsequently metabolized mainly via the glycolysis pathway, ...
Tanshinone ⅡA inhibits oral squamous cell carcinoma via reducing Akt-c-Myc signaling-mediated aerobic glycolysis[J]. Cell Death Dis, 2020, 11(5): 381. DOI:10.1038/s41419-020-2579-9 [14] Jiao L, Zhang HL, Li DD, et al. ...
The Metabolism of Carcinoma Cells When the problem of carcinoma is approached from the metabolic aspect, the first question which arises is: how does the metabolism of growing tissue differ from that of resting? The prospects of finding an answer to this question are goo... Warburg,O. - 《...
Activated oncogenes and loss of tumor suppressors contribute to reprogrammed energy metabolism and induce aerobic glycolysis, also known as Warburg effect. MicroRNAs are profoundly implicated in human malignancies by inhibiting translation of multiple mRNA targets. Using hepatocellular carcinoma (HCC) ...