Cell signaling under mechanical stimulus in specific cell typesdoi:10.1016/b978-0-12-817882-9.00005-7P. SundaramMechanotransduction
Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no currently available therapeutics. Prior evidence suggests that different cell types may play a role in CCM pathogenesis. The contribution of each cell type to the dysfun
Cell Communication and Signaling volume 19, Article number: 60 (2021) Cite this article 140k Accesses 33 Altmetric Metrics details Abstract Nuclear localization signals (NLS) are generally short peptides that act as a signal fragment that mediates the transport of proteins from the cytoplasm into ...
Understanding the molecular and cellular processes involved in lung epithelial regeneration may fuel the development of therapeutic approaches for lung diseases. We combine mouse models allowing diphtheria toxin-mediated damage of specific epithelial cell types and parallel GFP-labeling of functionally dividing...
Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no currently available therapeutics. Prior evidence suggests that different cell types may play a role in CCM pathogenesis. The contribution of each cell type to the dysfun
Summary:The migratory behavior of tracheal fusion cells is controlled by the FGF-induced expression of the transcription factor Escargot, which subsequently suppresses ERK signaling. 展开 关键词: Tubulogenesis Tip cell Cell migration FGF signaling ERK signaling ...
A TCF/LEF reporter cell line demonstrated the general ability of μdHACM to inhibit β-catenin induced transcription activity. Furthermore, in vitro systems, modeling elevated Wnt signaling, were developed in relevant cell types including tenocytes, synoviocytes, and human dermal fibroblasts (HDFs). ...
Understanding cell types and mechanisms of dental growth is essential for reconstruction and engineering of teeth. Therefore, we investigated cellular composition of growing and non-growing mouse and human teeth. As a result, we report an unappreciated cellular complexity of the continuously-growing mous...
Neurotransmitter, any of a group of chemical substances released by neurons to stimulate other neurons or muscle or gland cells. Signaling by neurotransmitters allows impulses to be passed from one cell to the next throughout the nervous system. Learn mo
epinephrine-stimulated cAMP synthesisIn cells the stimulatory effects of epinephrine are mediated through the activation of a second messenger known as cAMP (cyclic adenosine monophosphate). The activation of this molecule results in the stimulation of cell-signaling pathways that act to increase heart ...