Lack of pulmonary surfactant, related to mutations in genes critical for surfactant synthesis and activity, causes both acute respiratory failure and life-threatening chronic lung disorders, including pulmonary fibrosis (1, 2, 3, 4). Conversely, excess accumulation of surfactant lipids occurs in the ...
Two cases with major features of bowed long bones, hypertelorism, mandibular hypoplasia and hand and foot abnormalities with early neonatal death due to respiratory failure are presented. The radiologic and clinical findings are in keeping with oto-palato-digital syndrome type II and differ ...
P. jiroveciiis ubiquitous in the environment and causesasymptomatic infectionsin childhood Clinical Features ▪ Infantile form orplasma cell interstitial pneumoniaaffects malnourished children, who develop respiratory difficulty and failure ▪ Adult form affectsimmunocompromised patientswith impaired CD4-positiv...
Two cases with major features of bowed long bones, hypertelorism, mandibular hypoplasia and hand and foot abnormalities with early neonatal death due to respiratory failure are presented. The radiologic and clinical findings are in keeping with oto-palato-digital syndrome type II and differ significan...
a new focal functional defect (hemiplegia, aphasia, apraxia, hemianopsia or neglect) or a decrease of GCS at least 2 points, excluding other causes leading the secondary neurological deterioration (fever, infectious complications, hydrocephalus, seizures, respiratory failure, or electrolyte disorders)....
The problem with type 1 diabetes is that the person's cells are deprived of the sugar they need for energy. Without the insulin produced by the pancreas, sugar has difficulty entering the body's cells. Consequently, the body cells start burning fat for energy, which causes ketones to build...
All individuals with type 1 diabetes should have access to an uninterrupted supply of insulin; lack of access and insulin omissions are major causes of diabetic ketoacidosis Glucagon should be prescribed for all individuals with type 1 diabetes, and caregivers or family members should be instructed...
Respiratory failure, in fact, is the most common cause of death in SMA types 1 and 2. Noninvasive ventilation, including a BiPap machine, cough assist machine, and high-frequency chest wall oscillation, can be used to help clear mucus from the lungs. Sometimes mechanical ventilation and a ...
Klebsiellosis in infant squirrel monkeys has been associated with trauma, maternal neglect, and failure of hand-rearing (Moisson and Gysin, 1994). Klebsiella infection occurred primarily in young chimpanzees (Schmidt and Butler, 1971) and was one of the primary causes of respiratory disease deaths...
In contrast to the two previous mechanisms, this process is not cytotoxic. In this mechanism, attachment of the antibody to self-antigens, particularly receptors, leads to changes in the normal functions of the cell, which causes cellular dysfunction (Tak Mak and Jett, 2014). Examples of disea...