Alzheimer’s disease (AD) is an age-related neurodegenerative disorder that is characterized by the abnormal aggregation and accumulation of toxic peptides resulting in beta amyloid (Aβ) plaques and intracellular neurofibrillary tangles (NFT) [1]. According to recent reports, the number of patients...
Function of Nogo-A/Nogo-A receptor in Alzheimer’s disease. CNS Neurosci. Ther. 21, 479–485 (2015). Article CAS PubMed PubMed Central Google Scholar Llorens, F., Gil, V. & del Río, J. A. Emerging functions of myelin-associated proteins during development, neuronal plasticity, and ...
Function of Nogo-A/Nogo-A receptor in Alzheimer’s disease. CNS Neurosci. Ther. 21, 479–485 (2015). Article CAS PubMed PubMed Central Google Scholar Llorens, F., Gil, V. & del Río, J. A. Emerging functions of myelin-associated proteins during development, neuronal plasticity, and ...
Cardiovascular risk factors could affect the development of both types, but the extent of their influences would depend on the type of dementia. VD had a leading cause in most cases, such as ischemia, hemorrhage, anoxia, or hypoxia, while the causes of Alzheimer’s disease (AD) were not ...
Ketogenic diet prevents chronic sleep deprivation-induced Alzheimer’s disease by inhibiting iron dyshomeostasis and promoting repair via Sirt1/Nrf2 pathway. Front Aging Neurosci. 2022;14: 998292. Article CAS PubMed PubMed Central Google Scholar Luo P, Liu D, Zhang Q, Yang F, Wong YK, Xia ...
Finally, one study used diffusion tensor imaging (DTI) features coupled with WM integrity analysis to distinguish between late-onset bipolar disorder, Alzheimer’s Disease (AD) and HC. Using an SVM algorithm trained and tested on fractional anisotropy (FA), the authors achieved 100% accuracy in ...
The nature of the search of primary memory by persons with a presumptive diagnosis of mild Alzheimer's disease (DAT) was compared with that of normal elderly and young persons using the Sternberg(l 966) paradigm. DAT subjects evidenced a substantial deficit in the speed of scanning in primary...
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease. Cell153, 707–720 (2013). Article CAS PubMed PubMed Central Google Scholar Ousman, S. S. & Kubes, P. Immune surveillance in the central nervous system. Nature Neuroscience15, 1096–1101, ...
DNA methylation (DNAm) is one of the most widely studied epigenetic modifications that capture the cumulative effects of environmental and genetic factors. DNAm regulates cellular differentiation and gene expression and plays a key role in human development and disease etiology [1,2]. Single-nucleoti...
and disease [16,17]. Recently, increased lipidomic research has been conducted to identify biomarkers for and explain the cellular pathogenic processes of lipid metabolism abnormalities, which play a role in the pathogenesis of several diseases including T2DM, cancer, Alzheimer's disease, cardiovascular...