The regulation of IFN-Is in inflammation is a complex process that involves inducing cell-intrinsic antimicrobial states to limit the spread of infectious agents, modulating innate immune responses to inhibit cytokine production, and activating the adaptive immune system, which can lead to either restra...
mutations.12 Very recently, mutations in the CANT1 gene have also been found associated with the DBQD type 2, as well as with the so called 'Kim variant' of DBQD.13 CASE DESCRIPTIONS Case 1 The first son of a 26-year-old woman died a few days after delivery from respiratory failure...
COVID-19 clinical features include: asymptomatic course, upper respiratory tract symptoms, acute pneumonia and death [2]. The severity of the pulmonary involvement, with secondary respiratory failure, has required major hospitalization and/or admission to ICU. As a result of the COVID-19 pandemic,...
Pigeons infected with PPMV-1 show neurological, respiratory, and digestive symptoms, including moderate-to-severe depression with neck twist, ataxia, crouching, paralysis, eyelid edema, diarrhea, and green loose stools (Marlier and Vindevogel, 2006). According to the definition of the World ...
The healing pattern in flap surgeries is by primary intention, whereas in gingivectomy, it involves healing by secondary intention. These healing mechanisms involve the formation of a fibrin clot, which creates a framework for normal periodontal tissues to grow back. However, in patients with ...
Typically, the immune response to RSV is a type 1 response that involves both the innate and adaptive immune systems. However, type 2 cytokines may also be produced as a result of infection of RSV and there is increasing evidence that children who develop severe RSV-associated bronchiolitis are...
Of those who were excluded due to not reaching threshold suPAR levels (i.e., <6 ng/mL), a post hoc analysis revealed that only 2.9% of those patients progressed to respiratory failure or death, yet again highlighting the importance of suPAR as an early inpatient biomarker and major predicto...
Type II Diabetes involves the development of insulin resistance (i.e. a dampening of the metabolic response to insulin). What would the likely metabolic effects be of a person being hypersensitive to insulin? Type 1 and type 2 diabetes mellitus both result ...
Clearly, the recruitment and tissue-reparative stages must be closely regulated in the lung because excessive tissue injury or overexuberant tissue healing can significantly disrupt the pulmonary architecture and even lead to respiratory failure (3). In prolonged inflammatory diseases of the lung, ...
People with type 1 diabetes may experience more frequent infections of the skin or respiratory tract. Undiagnosed type 1 diabetes can become life threatening if a person goes intoketoacidosis(a state in which elevated blood sugar leads to other metabolic changes). ...