To investigate this, we first conducted a food intake screen in C. elegans and found that Atp6v0a1 expression is important in the regulation of food intake. Atp6V0a1 encodes a component of the vacuolar H + ATPase, a large multi-subunit enzyme proton pump that is involved in the ...
New FN3 domains designed in such a way can be used to screen for or select for optimized properties such as EGFR binding, solubility, stability, immunogenicity or serum half-life.Monospecific C-Met Binding MoleculesThe present invention provides fibronectin type III (FN3) domains that bind ...
The natural products were dissolved in dimethyl sulfoxide (DMSO) to 200, 100 or 50 μg/mL and the degree of binding to the LBD of PPAR-δ was quantified with fluorescence intensity using the LanthaScreen TR-FRET peroxisome proliferator receptor delta coactivator assay kit (Invitrogen, CA). DM...