Cushing’s syndromelaparoscopic surgeriesAdrenal-directed treatment for Cushing's disease should be considered when pituitary-directed treatment has not been successful. Bilateral adrenalectomy in this setting, although a secondary option, is a good treatment to decrease morbidity and mortality. Laparoscopic...
Surgery remains the principal treatment modality in Cushing's disease, but up to half of the patients might need additional treatment because of persistent or recurrent disease during their lifetime. Medical therapy plays an important role in control of hypercortisolemia in patients who are not ...
Cushing's disease is a type of Cushing's syndrome. It happens when there's a tumor in the pituitary gland, which makes your body produce too much cortisol. It's the most common kind of Cushing' syndrome that comes from inside the body, making up around 70% of cases. Questions for You...
Treatment of Cushing??s Disease in Childhood by Transsphenoidal Resection of a Pituitary MicroadenomaPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use...
Pasireotide and mifepristone: new options in the medical management of Cushing's disease To review and evaluate medical therapies for Cushing's disease (CD), with an emphasis on recent clinical trial experience with pasireotide and mifepristone, and to discuss the therapeutic potential and appropriate...
Krieger DT (1980) Cyproheptadine: Drug therapy for Cushing’s disease. In: Muller EE (ed) Neuroactive drugs in endocrinology. Elsevier/North Holland, Amsterdam, pp 361–370 Krieger DT, Luria M (1976) Effectiveness of cyproheptadine in decreasing plasma ACTH concentrations in Nelson’s syndrome....
The endocrinological, radiological, surgical, and pathological experience with 34 consecutive patients operated on for Cushing's disease is presented. Preoperative endocrine evaluation demonstrated that 19 patients had "typical" endocrine patterns for pituitary adrenocorticotropic hormone (ACTH)-dependent hyperco...
In hypercortisolism, adrenolytic therapy can be used diagnostically, as medical management prior to definitive therapy, or as adjunctive therapy for adrenocortical disease in which surgery has not led to a cure. The commonly ...
作者: S Kemink 摘要: The incidence of residual, functioning adrenal tissue in patients treated by total bilateral adrenalectomy for Cushing's disease is no t know n. Between 1962 and May 1988 50 patients w ith Cushing's disease were treated by bilateral adrenalectomy. Of these patients, 29...
medical issues,” said Mary Thanh Hai, M.D., acting director of the Office of Drug Evaluation II in the FDA’s Center for Drug Evaluation and Research. “By helping patients achieve normal cortisol levels, this medication is an important treatment option for adults with Cushing’s disease....