Mantle cell lymphoma (MCL) primarily affects older adults, accounting for 3-10% of all non-Hodgkin lymphoma (NHL) in western countries. The disease course of MCL is heterogenous; driven by clinical, cytogenetics, and molecular features that shape differences in outcomes, including proliferation ...
Mantle cell lymphoma (MCL) predominantly affects older adults, with a median age at diagnosis of 70 years. A frequently aggressive yet incurable lymphoma, the goal of therapy for MCL is to turn a potentially life-threatening illness into a chronic disease with prolonged periods of remission. Larg...
Andre Goy, MD, MS, chief, Division of Lymphoma, chairman and director, John Theurer Cancer Center, discusses the evolution of treatment in mantle cell lymphoma (MCL). Physicians have made significant progress in the treatment of patients with MCL, says Goy, but states that there is a ...
Mantle cell lymphoma is an aggressive subtype of non-Hodgkin B cell lymphoma that is characterized by a poor prognosis determined by Ki67 and Mantle Cell International Prognostic Index scores, but it is becoming increasingly treatable. The majority of patients, especially if young, achieve a progress...
Witzig TE. Current treatment approaches for mantle-cell lym- phoma. J Clin Oncol 2005;23(26):6409-14.Witzig TE. Current treatment approaches for mantle-cell lymphoma. J Clin Oncol. 2005; 23 :6409–6414.Witzig TE. Current treatment approaches for mantle-cell lymphoma - Review. Journal of...
Mantle cell lymphoma is a rare form of B-cell non-Hodgkin lymphoma. It is a type of blood cancer that affects white blood cells called lymphocytes.
Cyclophosphamide/Fludarabine (CF) is Active in the Treatment of Mantle Cell Lymphoma. Determines the efficacy and toxicity of the cyclophosphamide and fludarabine (CF) regimen in the treatment of mantle cell lymphoma. Patient characteristics... Cohen,J Bradley,Moskowitz,... - 《Leukemia & Lymphoma...
Credit: American Cancer Society: "Types of Non-Hodgkin Lymphoma." Mantle cell lymphoma is a malignant disease in which intensive treatment can prolong life. In a new study, scientists from Uppsala University and other Swedish universities show that people with mantle cell lymphoma who were unmarried...
Case description We present a case of a seventy-eight year-old man who developed vocal cord paralysis without any sign of peripheral neuropathy during the treatment of Mantle Cell Lymphoma. He first presented in 2008 with a few bilateral small inguinal lymph nodes. Inguinal lymph node biopsy demo...
Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma (NHL) which is one of the most aggressive lymphomas. Despite recent improvements in therapies, the development of therapy-resistance is still a major problem; therefore, in order to understand the molecular basis of therapy-resistance,...