Acute myeloid leukemia(AML, also called acute myelogenous leukemia) involves the rapid growth of myeloid cells. It occurs in both adults and children and affects about 19,500 people each year in the U.S. It is the most common form of aggressive leukemia in adults. ...
"Therapy for acute myeloid leukemia has barely changed in several decades. There is a huge need to discover better treatments for this aggressive disease. We've shown for the first time that targeting the pathways that our cells use to respond to oxygen levels could provide a new way to trea...
While better and safer treatments for acute leukemia are urgently needed, standard drug development pipelines are lengthy and drug repurposing therefore provides a promising approach. Our previous evaluation of FDA-approved drugs for their antileukemic activity identified disulfiram, used for the treatment...
We describe in details our regimens for induction chemotherapy and perform a review of existing literature concerning treatment of aggressive NK-cell leukemia. 展开 关键词: Internal Medicine Gastroenterology and Hepatology DOI: 10.1155/2011/818469 被引量: 3 ...
Researchers have identified a key weakness in acute myeloid leukemia, offering a promising new strategy to delay the progression of this aggressive blood cancer. The discovery focuses on disrupting the function of a certain protein complex that cancer cells, including leukemia cells, rely on to maint...
Acute myeloid leukemia induced by mitoxantrone treatment for aggressive multiple sclerosis. Acute myeloid leukemia (t-AML) is one of the worst adverse events of mitoxantrone treatment, but the exact risk in multiple sclerosis (MS) patients is not ... M Capobianco,S Malucchi,S Ulisciani,... -...
It is concluded that leukemia following germ cell tumors is increased in incidence and is likely to be treatment induced. Complete responses and long-term survival are possible in secondary leukemia and aggressive antileukemic therapy should be given. 展开 ...
the same as for adults. Chemotherapy and, in some cases, stem cell transplantation," explained Doctoral Researcher Denise Ragusa. "So, the hope would be that we could identify something that is specific to this particular type of leukemia so therapies are more effective and not as aggressive."...
Treatment of advanced extranodal NK/T cell lymphoma, nasal-type and aggressive NK-cell leukemia Extranodal NK/T cell lymphoma, nasal type (ENKL) with advanced stage and aggressive NK-cell leukemia (ANKL) are highly aggressive neoplasms with a dismal c... R Suzuki 被引量: 0发表: 0年 Upfro...
Until now, there has been no adequate treatment available for the rare and highly aggressive malignant blood disease T-PLL leukaemia. By screening blood samples from patients with haematological diseases, a team of doctors and researchers from MedUni Vie