The literature search was updated before preparing the final draft; no additional relevant publications were identified that might have required a change in the statements. Targets of treatment The treatment of obesity, i.e., the excessive accumulation of fat in the body, should be based on an ...
M Langer, M Cigada, M Mandelli, P Mosconi, G Tognoni Early onset pneumonia: a multicenter study in intensive care units Intensive Care Med, 13 (1987), pp. 342-346 View in ScopusGoogle Scholar 9 Y Berrouane, I Daudenthun, B Riegel, et al. Early onset pneumonia in neurosurgical intensiv...
Injuries other than road traffic accidents accounted for a major share of the DALYs in upper middle-income countries, which [...] daccess-ods.un.org 除道路交通事故之外的伤害占中上收 入国家(包括俄罗斯联 邦)和中低收入国家(包括中国)的残疾调整寿命年数的较大比例。 daccess-ods.un.org In...
As early as 1969, Arthur Prange recognized the importance of “enhancing” the efficacy of imipramine by adding thyroid hormone (L-triiodothyronine or T3) which was hypothesized to increase receptor sensitivity due to the interaction of the neuroendocrine system with depression [4]. In a pivotal ...
Sobota A, Graham DA, Heeney MM, Neufeld EJ. Corticosteroids for acute chest syndrome in children with sickle cell disease: variation in use and association with length of stay and readmission. Am J Hematol. 2010;85(1):24-28.PubMedGoogle Scholar 17. Sobota A, Graham DA, Neufeld EJ, ...
Alterations in the metabolic pathway of tyrosine, for example, lead to abnormal production of neurotransmitters like noradrenaline (NE) and dopamine (DA). This process results in an increase in the levels of trace amines, such as tyramine, octopamine, and synephrine. Such changes compromise ...
Increasing in frequency after age 65, PD sufferers exhibit a loss of dopaminergic (DA) neurons and decreased dopamine levels in the substantia nigra pars compacta that are responsible for its primary motor symptomology. Intraneuronal αSyn rich LBs characterize PD [39]. PD differs from other ...
Mofizul Islam M, Topp L, Conigrave KM, Day CA. Defining a service for people who use drugs as ‘low-threshold’: what should be the criteria? Int J Drug Policy. 2013;24(3):220-222. doi:10.1016/j.drugpo.2013.03.005 PubMedGoogle ScholarCrossref 31. Edland...
People are now living longer due to new innovations in both technology and modern medicine.1 The result has been a doubling of global life expectancy over the past century, and an increase in the a...
Microbial-based therapies have emerged as a promising frontier in cancer treatment. Traditional therapies often lack specificity and cause harmful side effects, necessitating more targeted approaches. Microorganisms naturally exhibit tumor-targeting properties and complex interactions with the tumor microenvironmen...