opportunities to develop improved phenotyping and better disease characterization.In clinical research,randomized controlled clinical trials are being complemented by large data collections in broad TBI populations in comparative effectiveness designs.Global collaborations are being developed among funding agencies,...
The NIDILRR can be a helpful resource for those with a disability from TBI or for caretakers of someone with TBI. TheNIDILRRfrequently offers educational materials, funding and grant opportunities, and insight into current research in TBI. Ultimately, it aims to help reintegrate individuals...
Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention. Brain Behav Immun. 2012;26(8):1191-1201.PubMedGoogle ScholarCrossref 38. Bryan CJ, Clemans TA. Repetitive traumatic brain injury, psychological symptoms, and suicide risk in a clinical sample of deployed ...
and is also associated with a heightened risk for mild traumatic brain injuries (mTBI). There is also concern that repeated-mTBI (r-mTBI) may have a long-term impact on developmental trajectories. Using an awake closed head injury (ACHI) model, that uses rapid head acceleration to induce a ...
Traumatic brain injury (TBI) is a common trauma with high mortality and disability rates worldwide. However, the current management of this disease is still unsatisfactory. Therefore, it is necessary to investigate the pathophysiological mechanisms of TB
Traumatic axonal injury: mechanisms and translational opportunities. Trends Neurosci. 2016;39(5):311-324. doi:10.1016/j.tins.2016.03.002 PubMedGoogle ScholarCrossref 49. Narayana PA, Yu X, Hasan KM, et al. Multi-modal MRI of mild traumatic brain injury. Neuroimage...
Our knowledge of the pathophysiology about traumatic brain injury (TBI) is still limited. Neutrophils, as the most abundant leukocytes in circulation and the first-line transmigrated immune cells at the sites of injury, are highly involved in the initiat
Regenerative repair of the brain after traumatic brain injury (TBI) remains an extensive clinical challenge, inspiring intensified interest in therapeutic approaches to explore superior repair strategies. Exosome therapy is another research hotspot follo
Finally, we review the limitations and health economics of traumatic brain injury, and whether future gene delivery approaches will be viable for patients and health care systems. Main text Traumatic brain injury (TBI) is a major cause of global morbidity and mortality. Causes of TBI range from...
This normative database comprised of 231 participants (48.5% women) aged between 60 and 90 years and was derived from the Alzheimer’s Disease Neuroimaging Initiative grand opportunities (ADNI-GO) study [39]. The AI is defined as the ratio of left-right volume difference divided over the ...