For yellow, grade 5 corresponds to wild-type pigmentation; grades 4 and 3 correspond to partial stimulation of the yellow gene by enhancers; grade 2, to the basal level of yellow expression in the absence of enhancers; grade 1, to complete loss of yellow expression.The pigmentation scores ...
The arrows indicate the direction of changes in histone modification and gene expression after Gata3 deletion. The p values of either increased or reduced gene expression correlated with a change in histone modification are indicated. To examine whether the changes in H3K4me2 at the GATA3 sites ...
but they had different regulatory patterns. SOX2 and MYC were up-regulated in NSE, whereas POU5F1 and KLF4 had down-regulation. Second, the number of regulation pairs of these four factors varied. KLF4 and MYC had high degree in the network (3 and 6 folds, respectively) in SE, while SO...
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(2009). Three panels, ordered from rostral to caudal, are shown for each seed voxel Full size image Fig. 3 Expression of specific genes in different areas of the thalamic complex. a Expression profile matrix of thalamic complex nuclei. b In situ hybridization data for two selected mRNAs that...
proliferationandapoptosisviainhibitingSTAT 3/microRNA21畅WP1066providednewdirectionand possibilitytohumantonguesquamouscellcarcinomatherapy. 【Keywords】Oralsquamouscellcarcinomac;Tongueneoplasms;Cellproliferation;Apoptosis 舌鳞状细胞癌是原发性口腔癌中最常见的病理 类型,发病率占口腔癌的43畅4% [1] ,寻找更有效的...
ameliorates obesity and obesity-induced metabolic syndrome in HFD-fed wild-type mice but not ATF3−/−mice. ST32db treatment of 3T3-L1 adipocytes suppresses lipogenesis/adipogenesis through the ATF3 pathway to directly inhibit C/EBPα expression and indirectly inhibit the CHOP pathway. Overall,...