Focusing on the human therapeutic experience, this analytical review will review the biology of mechanisms of action, the limiting factors contributing to disease restriction in therapeutic efficacy, and the mechanism and frequency of treatment-limiting adverse responses of TNFα antagonists. It is hoped...
factor; Macrophage cytotoxic factor; MCF; Necrosin; TNF a; TNF-alpha; TNF; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precurso; Tumour Necrosis Factor Alpha; TNFA_HUMAN.靶点:详见...
I Fomin,D Caspi,V Levy,... - 《Annals of the Rheumatic Diseases》 被引量: 618发表: 2006年 Therapeutic antibodies elicited by immunization against TNF-alpha. Tumor necrosis factor-alpha (TNF-alpha) is critically involved in the pathogenesis of several chronic inflammatory diseases. Monoclonal anti...
morphinehuman microgliaThe cytokine tumor necrosis factor alpha (TNFα) is a key factor in several inflammatory diseases and its levels increase in response to a variety of internal or external stimuli. The regulation of...doi:10.1007/s11481-008-9137-zBassel E. Sawaya...
Plasma levels of TNF-alpha soluble receptors correlate with outcome in human falciparum malaria. Plasma from immune (residents of malaria infested areas) and non immune (European travellers) patients suffering from cerebral malaria, severe or mild, was... P Deloron,LP Roux,P Ringwald,... - 《...
Size:50ul Concentration:1mg/ml Applications:WB(1:500-2000)ELISA(1:5000-10000)Flow-Cyt(1ug/Test) Cross Reactive Species:HumanMouse 本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断用! 关键字: TNFalpha;APC1;Cachectin;DIF;TNFSF2;TNFA;TNF alpha;公司...
The CD14(+) monocyte fraction of human peripheral mononuclear cells was cultured with TNFalpha +/- IL-1alpha in the presence of M-CSF. TNFalpha induced the formation of multinucleated cells (MNCs) which were positive for TRAP, VNR and cathepsin K and showed evidence of resorption pit ...
Sample-dependent, Check data in validation data gallery. 产品信息 CL594-60291 targets TNF-alpha in IF-P applications and shows reactivity with human samples. Tested Applications IF-P Application Description Tested Reactivity human Immunogen TNF-alpha fusion protein Ag11413 种属同源性预测 Host / ...
TNF alpha Antibody (AHC3712) in ELISA The Journal of experimental medicine 1999 - Figure 3 CT treatment selectively suppressed IL-12 p70 and TNF-alpha, but not IL-10, TGF-beta 1 , or IL-6. Human monocytes (2 x 10 6 cell/mL) were stimulated with SAC (0.01%) and IFN-gamma (100...
Tumour necrosis factor alpha (TNF-alpha) is a pro-inflammatory cytokine with various roles in inflammatory processes. Several TNF blockers are currently approved for use in rheumatoid arthritis (RA) as well as in other inflammatory arthropathies. The latest of these compounds is the human monoclon...