TLR4/MyD88/NF-kappa B signaling pathwayCoronary microembolization (CME) is a common complication during the treatment of acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI). Nicorandil can be used to prevent myocardial injury after PCI to reduce the incidence of coronary no-...
研究发现,辐射作为一种外源性危险信号分子可以激活TLR4,激活的TLR4通过髓样分化因子(myeloid differentiation factor 88, MyD88)依赖途径进一步激活核因子κB(nuclear factor kappa-B,NF-κB)等转录因子,最终促进促炎因子白细胞介素-6(inter...
TLR4-MyD88-TRAF6-TAK1 Complex-Mediated NF-κB Activation Contribute to the Anti-Inflammatory Effect of V8 in LPS-Induced Human Cervical Cancer SiHa Cells TLR4 - MyD88 - TRAF6 - TAK1 Complex - Mediated NF-资B Activation Contribute to the Anti - Inflammatory Effect of V8 in LPS-Induced ...
TLR4 主要通过两个信号通路对肿瘤细胞凋亡进行调节,其一为 TLR4 通过 MyD88 蛋白调节核转录因子 kappaB(NF-κB)产生,促进肿瘤细胞增殖;其二为 TLR4 通过 PI3K/Akt 信号通路来抑制肿瘤细胞凋亡。 现就近年来TLR4 与肿瘤细胞凋亡相关性的研究进行综述。 【关键词】 Toll 样受体 4(TLR4); 肿瘤; 凋亡; 进展中图...
Sevoflurane treatment enhanced the phosphorylation of NF-kappa B, and up-regulated the expressions of TLR4 and MyD88 (P < 0.05), which demonstrated that sevoflurane inhibited proliferation and differentiation of neuronal cells by activating TLR4/MyD88/NF-kappa B signaling both in vitro and vivo. ...
参与通路 activation of MAPK activity toll-like receptor signaling pathway B cell proliferation involved in immune response nitric oxide production involved in inflammatory response regulation of dendritic cell cytokine production MyD88-dependent toll-like receptor signaling pathway MyD88-independent toll-like...
The mRNA expression levels of MyD88 and NF-kappa B were obviously higher in pre-hibernation than those of the breeding period. These findings suggested that TLR4/MyD88 signal pathway might participate in the oviductal functions of Rana dybowskii during the breeding period and pre-hibernation.Zhang...
NLRP1NLRP3 inflammasomesMonocytesPreeclampsiaProgesteroneVitamin DThis study evaluated the in vitro modulatory effect of progesterone (PG) and vitamin D (VD) on NLRP1/NLRP3 inflammasomes and TLR4/NF-kappa B pathway in monocytes from pregnant women with preeclampsia (PE). Monocytes from 20 preeclamp...
The mRNA expression levels of MyD88 and NF-kappa B were obviously higher in pre-hibernation than those of the breeding period. These findings suggested that TLR4/MyD88 signal pathway might participate in the oviductal functions of Rana dybowskii during the breeding period and pre-hibernation.Zhang...
Rat IgG2a kappa Isotype Control (eBR2a), PE-Cyanine7, eBioscience™ 分类 Monoclonal 类型 Antibody 克隆号 MTS510 偶联物 PE-Cyanine7 Request custom conjugation 激发/发射光谱 569/780 nm查看光谱 形式 Liquid 浓度 0.2 mg/mL 纯化类型 Affinity chromatography ...