1 Thioredoxin-dependent peroxidases (peroxiredoxin) are considered to be members of a family of proteins reducing intracellular hydrogen peroxide (see [41] in this volume5). In addition, several thioredoxin-related proteins have been reported. Nucleoredoxin is a nuclear protein.6 TRP32 is a ...
Our work shows that TrxP-1 is more effective than selenium-dependent glutathione peroxidase in protecting cells against H2O2 damage. Transfection of mouse WEHI7.2 lymphoma cells with human TrxP-1 or TrxP-2, but not TrxP-4, protects the cells against H2O2 induced apoptosis but does not ...
By contrast, although TRX1 suppression decreased proliferation of androgen-dependent LNCaP SB0 and VCaP cells, the extent of this growth inhibition was far less (Fig. 2e; Supplementary Fig. 2c) than in CRPC lines. We could not assess growth defects in CSS culture for these lines, as they...
After extensive washing, the membranes were incubated with polyclonal goat anti-rabbit IgG antibody (1:2000 by volume) conjugated with horseradish peroxidase. The membranes were washed in PBS, and the chemiluminescent substrate was added. The membranes were stripped and stained with Coomassie Blue R-...
硫氧还蛋白过氧化物酶(Thioredoxin peroxidase,TPx)是过氧化物氧还蛋白(Peroxiredoxin,Prx)家族的一员,是一种巯基特异性的抗氧化蛋白,用于清除机体正常细胞产生的过量的活性氧。3. multiceps thioredoxin peroxidase(TmTPx) cDNA fragment was amplified by RT-PCR from the total RNA,ligated into pMD18-T vector...
(500 μΜ) for 48 h. Sal increased the cell viability of SH-SY5Y cells treated with MPP+in a dose-dependent manner. Moreover, Sal did not show cytotoxic effects on SH-SY5Y cells even at 50 µM (Table1). Morphological alterations of the cells were also observed under an inverted ...
PRDX2, Recombinant, Human (Peroxiredoxin-2, Thioredoxin Peroxidase 1, Thioredoxin-dependent Peroxide Reductase 1, Thiol-specific Antioxidant Protein, TSA, PRP, Natural Killer Cell-enhancing Factor B, NKEF-B, TDPX1, NKEFB)供应商 USBiological产品...
cytosolicthioredoxinperoxidase硫氧还蛋白过氧化物hydroperoxide cTPxI,cTPxIIandorganichydroperoxidedetoxificationCYTOSOLICTHIOREDOXINPEROXIDASEIANDIIAREIMPORTANTDEFENSESOFYEASTAGAINSTORGANICHYDROPEROXIDEINSULT.CatalasesandperoxiredoxinscooperateinthedecompositionofH2O2byyeastDanielaCristinaMunhoz1andLuisEduardoSoaresNetto1,*1Depart...
1.Expression,purification and activity characterization of a thioredoxin peroxidase from Branchiostoma belcheri Tsingtaunese;中国青岛文昌鱼硫氧还蛋白过氧化物酶表达、纯化及活性特征 2.multiceps thioredoxin peroxidase (TmTPx) cDNA fragment from Coenurus cerebralis isolated from naturally infected sheep in Jing...
Second, TXL-1 activity is delayed in time when compared to that of TRX-1. TXL-1 starts to show the enzymatic activity after 45 min of initiating the assay, when TRX-1 has already reached its maximal activity. This long latency phase explains the failure to detect TrxR-dependent activity ...