硫氧还蛋白过氧化物酶(Thioredoxin peroxidase,TPx)是过氧化物氧还蛋白(Peroxiredoxin,Prx)家族的一员,是一种巯基特异性的抗氧化蛋白,用于清除机体正常细胞产生的过量的活性氧。 3. multiceps thioredoxin peroxidase(TmTPx) cDNA fragment was amplified by RT-PCR from the total RNA,ligated into pMD18-T vector...
Goyer A, Haslekas C, Miginiac-Maslow M, Klein U, Le Marechal P, Jacquot JP, Decottignies P. 2002. Isolation and characterization of a thioredoxin-dependent peroxidase from Chlamydomonas reinhardtii. Eur. J. Biochem. 269:272-282. http://dx.doi.org/10.1046/j.0014-2956 .2001.02648.x....
(Li et al., 2021). Meanwhile, Zhou et al. found that Trx-1 overexpression could improve behavioral deficits by regulating glutathione peroxidase 4 and glutathione to inhibit iron sagging in patients with Parkinson's disease (Zhou et al., 2008). Therefore, exploring the targets of Trx-1 ...
Apart from TXNPx Type I belonging to the classical decameric 2-cys peroxiredoxins, a new class of monomeric tryparedoxin-dependent peroxidase with non-selenium glutathione peroxidase-like activity (TXNPx Type II) has been identified inL. major(Konig and Fairlamb, 2007),T. cruzi(Wilkinson et ...
The protein is homologous to thioredoxin peroxidase and other antioxidant proteins. ... S Watabe,T Hiroi,Y Yamamoto,... - 《Febs Journal》 被引量: 184发表: 2010年 Localization of TDPX1, a human homologue of the yeast thioredoxin-dependent peroxide reductase gene (TPX), to chromosome 13q12 ...
the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin,thioredoxin reductase,and NADPH as a reducing system. Mammalian Prxs are 20 – 30 kDa in molecular size and vary in subcellular localization: Prx I,II,and VI in cytosol,Prx III in...
glutamicum PrxQ can prevent the damaging effects of adverse stresses by acting as thioredoxin-dependent monomeric peroxidase could be further applied to improve the survival ability and robustness of the important bacterium during fermentation process. 展开 关键词: PEROXIREDOXINS OXIDATIVE stress ...
change of cell growth phenotype has been suggested to be one of the oncogenic transformation processes.80The expression of TBP-2 is lost in HTLV-I-positive IL-2-independent T-cell lines, but maintained in HTLV-I-positive IL-2-dependent T-cell lines as well as HTLV-I-negative T-cell ...
(redox regulation). Members of the TRX system regulate apoptosis through a wide variety of mechanisms. A family of thioredoxin-dependent peroxidases (peroxiredoxins) protects against apoptosis by scavenging hydrogen peroxide. Thioredoxin 2 is a critical regulator of cytochromecrelease and mitochondrial ...
Peroxiredoxin 4 (Peroxiredoxin-4, PRDX4, PRX-4, Peroxiredoxin IV, Prx-IV, Antioxidant Enzyme AOE372, AOE37-2, Thioredoxin Peroxidase AO372, Thioredoxin-dependent Peroxide Reductase A0372) 供应商 MyBioSource 产品货号 MBS618043 产品报价 ￥询价/0.05mL ￥询价/5x0.05mL ￥询价/其它规格 ...