Understanding the mechanisms by which CSCs contribute to cancer progression can help to provide novel therapeutic approaches against solid tumors. In this line, the effects of mechanical forces on CSCs such as epithelial-mesenchymal transition, cellular plasticity, etc., the metabolism pathways of CSCs...
& Negelein, E. The metabolism of tumors in the body. J. Gen. Physiol. 8, 519–530 (1927). Article CAS PubMed PubMed Central Google Scholar Moreira, J. D. et al. The redox status of cancer cells supports mechanisms behind the Warburg effect. Metabolites 6, pii: E33 (2016). ...
Due to persistence of hyper-metabolism she was submitted to thyroid surgery. The histology revealed a toxic adenoma. The results were explained in the light of the work of Warburg on quantization of cell respiration [71], [72]. In 1961 Wiswell studied the effects of 1.0 g magnesium sulfate...
Retinoic acid(RA) is the most important metabolite of vitamin A, which plays crucial roles in cell differentiation, growth as well as maintaining the funct... WU Han-Han,C Wang,HU An-La,... 被引量: 0发表: 2018年 The Metabolism of Tumors in the Body MAASSEN AP. O Warburg,F Wind,EI...
Brain metastasis (BrM) poses a significant challenge to the prognosis and quality of life for patients with non-small cell lung cancer (NSCLC). Gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the central nervous system (CNS), has been i
leader cells in the invasive front will enhance the energy status to respond to the higher metabolic costs for ECM remodeling while moving forward compared to the cells behind the tumor center [6,7]. However, whether similar leader cells with strong metabolism exist in the tumor margin of OSCC...
Human body has its immune operation to protect us from the internal threats (such as malignant cells) which was called the tumor immune cycle1. In this cycle, effector T lymphocytes will infiltrate into tumors and kill them. However, some essential steps for T cell immunosurveillance are often...
They report studies of the respiration in ova of sea urchins, human erythrocytes, and the red blood cells of frogs, birds and rabbits. The remaining twenty (1923-1929) are studies of the metabolism of tumors. No change has been made in reproducing the original articles other than translation...
O. et al. The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type. Cell Metab. 15, 157–170 (2012). Article CAS PubMed PubMed Central Google Scholar Mayers, J. R. et al. Tissue of origin dictates branched-chain amino acid metabolism in mutant ...
"Obviously, thelocal environmentaffects the cancer cells more than previously known. The metastatic tumors should show the same metabolic properties no matter where in the body they are located, but we discovered that the cancer cells largely adapted their metabolism to the new tissue in order to ...