and impairments of its function are directly associated with a variety of metabolic diseases, including obesity, cardiovascular diseases, type 2 diabetes mellitus (T2DM), and cancer.15,16Historically, two types of distinct mature adipocytes—white and brown...
Related to Metabolic diseases:metabolic syndrome,diabetes mellitus,diabetes ThesaurusAntonymsRelated WordsSynonymsLegend: Switch tonew thesaurus Noun1.metabolic disorder- a disorder or defect of metabolism disorder,upset- a physical condition in which there is a disturbance of normal functioning; "the docto...
Crohn’s disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary habits over the past few decades. Here, we review experimental and clinical evidence for the metabolic nature of gut ...
However, the mechanism of action of metformin is still being investigated [41]. Pyruvate Metabolism: Connecting Cardiovascular Diseases to Cancer If a therapeutic approach has already been established in another disease and its metabolic overlap with cancer is clear, why should we not jump straight ...
PreventionDAYTIME NAPPING, DAYTIME SLEEPINESS AND THE RISK OF METABOLIC DISEASES: DOSE-RESPONSE META-ANALYSIS USING RESTRICTED CUBIC SPLINE MODEL Author links open overlay panelTomohide Yamada, Shojima Nobuhiro, Kadowaki TakashiShow more Add to Mendeley Share Cite...
The synergy between the human immunodeficiency virus (HIV) and Mycobacterium tuberculosis during co-infection of a host is well known. While this synergy is known to be driven by immunological deterioration, the metabolic mechanisms that contribute to th
ContextThe metabolic syndrome has been identified as a target for dietary therapies to reduce risk of cardiovascular disease; however, the role of diet
The inflammasome is a protein complex that comprises an intracellular sensor (typically a Nod-like receptor), the precursor procaspase-1 and the adaptor ASC. Inflammasome activation leads to the maturation of caspase-1 and the processing of its substrate
CIC is believed to be a key player and may serve as a novel therapeutic target in types of human metabolic diseases. Therefore, in this paper, we integrally described the structure and function of CIC. Then, we gave an overview of CIC related diseases including cancers, congenital diseases, ...
More information:Norbert Stefan et al, Metabolic health and cardiometabolic risk clusters: implications for prediction, prevention, and treatment,The Lancet Diabetes & Endocrinology(2023).DOI: 10.1016/S2213-8587(23)00086-4 Journal information:The Lancet Diabetes & Endocrinology ...