The alarming number of recently reported human illnesses with bacterial infections resistant to multiple antibacterial agents has become a serious concern in recent years. This phenomenon is a core challenge for both the medical and animal health communi
MaSat HOR structure. A: The dot plot of the MaSat array N707 (Additional file 2); a window size is 13 bp, sequence similarity is shown in gray scale. HOR units are shown as arrows with indicated length; smaller arrows indicate HOR subunits; different colors and letters indicate subunits va...
Chemokines are an indispensable component of our immune system through the regulation of directional migration and activation of leukocytes. CXCL8 is the most potent human neutrophil-attracting chemokine and plays crucial roles in the response to infecti
S6C) while it increased the resting period (Additional file 1: Fig. S6D). Interestingly, verapamil decreased the contraction homogeneity of the isogenic control hiPSC-CMs (Additional file 1: Fig. S6E). Such a reduction in the contraction homogeneity is thought to be dysfunctional as we have ...
Nephrogenesis is characterized by the mesenchymal to epithelial transition (MET) of future nephron cells, while podocytes also display a reverse process of epithelial to mesenchymal transition (EMT) at later developmental stages1. Podocytes are the key cells in formation of glomerular basement membrane...
However, the mechanism by which the metal specificity of LIV-1 proteins is determined remains poorly characterized. Our previous work identified that a LIV-1 subfamily member, Drosophila ZIP13 (dZIP13), was responsible for dietary iron absorption and essential for fly development [18]. We ...
Noun1.latent period- the time that elapses between a stimulus and the response to it reaction time,response time,latency interval,time interval- a definite length of time marked off by two instants 2.latent period- the time that elapses before the presence of a disease is manifested by symp...
Cell division is characterized by sequential halving of CFSE fluorescence, generating equally spaced peaks on a logarithmic scale; peaks indicate the division cycle number. Similar results of MTT colorimetric assay were obtained using CSFE-DA methodology, which accurately confirmed proliferation rate of ...
Type 2 diabetes mellitus (T2DM) is a major public health problem with more than 400 million people affected in the world. This chronic metabolic disorder is characterized by hyperglycemia secondary to the decline of β-cell secretory function and mass (e.g., β-cell failure) and is usually ...
(median half-life about 7 h), translation inhibition by RocA for such a short period (30 min) would not result in reduction of protein abundance that is detectable by regular mass-spectrometry or western blotting, especially for the proteins with high abundance such as ribosome proteins ...