A signature characteristic of stem cells is their ability to self-renew, affording a theoretically limitless ability to produce daughter cells and their descendents. This near-timeless dimension of stem cell function is not free of the constraints of pla
hematopoietic stem cellhematopoietic activityplacental HSCshematopoietic microenvironmentThe placenta is a highly vascularized organ that mediates fetal-maternal exchange during pregnancy and is thereby vital for the survival and growth of the developing embryo. In addition to having this well-established role...
百度试题 题目the hematopoietic stem cell originate from: A.neural crestB.somatopleureC.neural tubeD.mesodermE.york sak相关知识点: 试题来源: 解析 E 反馈 收藏
GB Adams, DT Scadden The hematopoietic stem cell in its place Nat Immunol, 7 (4) (2006), pp. 333-337 CrossrefView in ScopusGoogle Scholar 2 A Wilson, E Laurenti, G Oser, et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair [publi...
Finding the Hematopoietic Stem Cell Niche in the Placenta The origin of definitive hematopoiesis poses a fundamental biological question. In this issue of Developmental Cell, two groups have independently found a ... L Li - 《Developmental Cell》 被引量: 28发表: 2005年 Analysis of the Mouse Pla...
Hariman H. The hematopoietic stem cell transplantation in Indonesia: an unsolved dilemma. Bone Marrow Transplant 2008; 42: S85-S88.Hariman H. The hematopoietic stem cell transplantation in Indonesia: an unsolved dilemma. Bone Marrow Transplant 2008; 42:85-88....
PURPOSE OF REVIEW: Hematopoietic stem cells are thought to reside in discrete cellular spaces termed "niches." The cellular elements and matrix surrounding the stem cell within the niche constitute the microenvironment. The purpose of this review is to discuss recent reports that have begun to eluci...
长期以来,研究人员推测癌细胞的表型异质性(phenotypic heterogeneity)可能源于发生驱动突变的细胞类型,也就是 “细胞起源(cell-of-origin)” 模型。然而,传统的研究方法就像戴着一副模糊的眼镜,无法清晰地分辨干细胞和祖细胞中克隆异质性的亚群。特别是对于造血干细胞(hematopoietic stem cells,HSCs),尽管它处于造血层级...
长期以来,研究人员推测癌细胞的表型异质性(phenotypic heterogeneity)可能源于发生驱动突变的细胞类型,也就是 “细胞起源(cell-of-origin)” 模型。然而,传统的研究方法就像戴着一副模糊的眼镜,无法清晰地分辨干细胞和祖细胞中克隆异质性的亚群。特别是对于造血干细胞(hematopoietic stem cells,HSCs),尽管它处于造血层级...
The implications of stem cell heterogeneity for disease pathogenesis and therapy are poorly defined. JAK2V617F myeloproliferative neoplasms (MPNs), harboring the same mutation in hematopoietic stem cells (HSCs), display diverse phenotypes, including polycythemia vera (PV), essential thrombocythemia (ET...