Somatostatin modulates the function of Kupffer cells[J] . Tzu-Chieh Chao,Hsiao-Hsiang Chao,Miin-Fu Chen,Jen-Der Lin.Regulatory Peptides . 1997 (3)Chao Te, Chao HH, Chen MF & Lin D (1997) Somatostatin modulates
活Kupffer细胞免疫功能,增强机体抵抗能力。 关键词:白术多糖;Kupffer细胞;激活作用 doi:10.3969/j.issn.1004‐2407.2013.06.019 中图分类号:R965文献标志码:A文章编号:1004‐2407(2013)06‐0607‐04 ActivationoftheimmunologicfunctionofmiceKupffercellsbythepolysaccharide ofAtractylodesmacrocephalaKoidz JIAOYan 1,TANGNa...
(cGAMP) synthase (cGAS)-stimulator of interferon genes (STING) pathway, downstream signals can control the production of type I interferon and nuclear factor kappa-light-chain-enhancer of activated B cells to promote the activation of pro-inflammatory molecules, which are mainly induced during ...
In fact, with high rates of obesity (likely one of the most important drivers) and type 2 dia- betes mellitus (T2DM) among adult patients, which are associated with an aging population, NAFLD mortality is reported to steadily increase. Specifically, in the United States, the estimated ...
Hepatic macrophages (macs) have been implicated in this process, being activated to become pro-inflammatory by the excess lipids and damage in the fatty liver and by signals originating from the intestine. However, it is not clear which macs are involved. Kupffer cells (KCs) are the main mac...
However, without the function of dectin-1 and Card9, the growth of fungi may out of control and promote inflammatory cell infiltration, this make mice take on high risk of IBD. In addition, there are two points we need to take notice, firstly, Fungi have nothing to do with inflammation,...
ofKupffer cells and their interactions with Plasmodiumsporozoites in the context of a model in which thesehepatic macrophages function as the sporozoite gateto the liver.The pre-erythrocytic phase of the Plasmodium lifecyclePlasmodium sporozoites are transmitted by femaleanopheline mosquitoes which deposit ...
②Science:Neurodegeneration enters the era of functional genomics 观点:神经退行性疾病进入了功能基因组学时代 DOI: 10.1126/science.adk5693 ③Science:Kupffer cell–like syncytia replenish resident macrophage function in the fibrotic liver 库普弗细胞(KC)样合胞体补充纤维化肝脏中驻留的巨噬细胞功能 ...
Other important components of NAFLD-NASH pathogenesis, whose expression by infiltrating macrophages and resident Kupffer cells is induced subsequently to barrier deterioration are inflammatory cytokines such as IL-6 and TNF (Nakagawa et al., 2014; Naugler et al., 2007; Park et al., 2010). The ...
11. The antisense oligonucleotide according to claim 7, wherein said lymphoma is a non-Hodgkin's lymphoma. 12. The antisense oligonucleotide according to claim 3, wherein said leukaemia is acute myeloid leukaemia or chronic myeloid leukaemia. 13. An antisense oligonucleotide of between 7 and ...