Objective To construct a hyaluronidase (hyl) gene mutant strain of Enterococcus faecium and to study the function of hyl gene.Methods An isogenic hyl-defieient mutant (* hyl) with suicide plasmid pTX4577 was constructed and screened by allelic replacement.The mutant strain and wild type strain ...
It has long been predicted that the members of the hyaluronidase enzyme family have important non-enzymatic functions. However, their nature remains a mystery. The metabolism of hyaluronan (HA), their major enzymatic substrate, is also enigmatic. To examine the function of Hyal2, a glycosyl...
enzyme (redirected fromEnzyme induction) Thesaurus Medical Legal Financial Encyclopedia en·zyme (ĕn′zīm) n. Any of numerous compounds that are produced by living organisms and function as biochemical catalysts. Some enzymes are simple proteins, and others consist of a protein linked to one or...
aThe enzyme hyaluronidase catalyzes the hydrolysis of the main intersti-tial constituent, increasing tissue permeability and helpingthe venom spread. 酵素玻璃酸摧化主要细胞间的组成部分、增长的组织渗透性和helpingthe毒液传播的加水分解。[translate]
et al. Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing. Cell 132, 89–100 (2008). CAS PubMed PubMed Central Google Scholar Korennykh, A. V. et al. The unfolded protein response signals through high-order assembly of Ire1....
The effect of hyaluronic Acid on the invasiveness of malignant glioma cells: comparison of invas... Hyaluronidase (HAse), a degrading enzyme of hyaluronic acid (HA), is highly expressed in patients with malignant glioma. The purpose of this study was to v... SG Jin,YI Jeong,S Jung,......
We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some...
The in vivo function of GAME36 was examined by generating loss-of-function mutants in the cultivated tomato using CRISPR-Cas9 genome editing (Fig.4aand Supplementary Fig.12). Homozygousgame36mutant lines were analyzed for the altered SGA profiles. We could not detect acetoxytomatine and acetoxy-...
significantly higher than that of the control; the activities of the corresponding antioxidant enzymes, i.e., T-SOD, CAT, and GPX, in the lead group were significantly lower than those in the control group; and the activity of GST in the phase-II metabolism enzyme had significantly decreased...
Remarkable progress in ageing research has been achieved over the past decades. General perceptions and experimental evidence pinpoint that the decline of physical function often initiates by cell senescence and organ ageing. Epigenetic dynamics and immu