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aneuploidy causes widespread proteotoxicity, irrespective of the chromosome involved (Oromendia et al.2012). Moreover, the proteotoxicity resulting from a single extra chromosome leads to a decrease in yeast replicative lifespan, the extent of which is proportionate to the size...
(CRISPR)/Cas9 system-mediated gene-editing technology has been widely used in research into the genetic breeding of animals, the system’s efficiency at inserting foreign genes is not high enough, and there are certain off-target effects; thus, it is not appropriate for use in the genome ...
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Receptor tyrosine kinase (RTK) is a membrane tyrosine kinase that could be activated by binding ligands with the extra- cellular domain, and communicating signals according to the tyrosine kinase activity of the intracellular domain. Recent studies revealed that RTKs such as EGFR, PDGFR and MET ...
Finally, since the prey are stationary, we model the effects of hypoxia as creating extra prey mortality in Patch 1. An additional source of prey mortality that we do not model is the possibility that hypoxic conditions can increase prey susceptibility to predators by decreasing their burial ...