Cancer metastasis to bone is a three-dimensional(3D), multistep, dynamic process that requires the sequential involvement of three microenvironments, namely, the primary tumour microenvironment, the circulation microenvironment and the bone microenvironment. Engineered 3D approaches allow for a vivid recapi...
Biomaterials and engineered microenvironments to control YAP/TAZ-dependent cell behaviour. Nat. Mater. 17, 1063–1075 (2018). Article ADS CAS PubMed PubMed Central Google Scholar Trepat, X. et al. Universal physical responses to stretch in the living cell. Nature 447, 592–59 (2007). ...
PS-039-Role of ductular reaction on the hepatic microenvironment in chronic liver diseasedoi:10.1016/S0618-8278(19)30045-3Silvia Ario MonsBeatriz Aguilar-BravoMar CollEster Garcia-PrasPau Sancho-BruElsevier BVJournal of Hepatology
ADC targets can be present either on tumour cells, tumour-associated cells (e.g. tumour endothelial cells) or in the tumour microenvironment [11]. Ideally the ADC target is highly overexpressed with limited heterogeneity at the cell membrane of tumour cells but is not, or only very limited, ...
alteration of which was associated with development of different human cancers; for example, the MIF signaling pathway was able to upregulate expression of various cancer-promoting genes, which can not only act directly on tumors, but also promote tumorigenesis by acting on tumor microenvironment [36...
Conclusion: The new program of tertiary prevention for liver cancer based on"tonifying the kidney to promote liver regeneration and repair by affecting stem cells and their microenvironment"can play a role in regulating liver cancer cells and their microenvironment, which reflects the advanced ...
In recent years, the continuous development of innovative nanopharmaceuticals is expanding their biomedical and clinical applications. Nanomedicines are be
The Aventis Company (vitamin B12 production leader) prefers to useP. denitrificans(which lacks the status) for the industrial production of cobalamin. Vitamin B12 biosynthesis byP. denitrificans, contrary toP. freudenreichii, takes place in pure aerobic conditions. The combination of genetic engineering...
Active ingredients of TCM act on immune cells to balance the immune microenvironment. This increases the theoretical feasibility of subsequent studies of the active ingredients of TCM as immune adjuvants. It is crucial to apply AS models to study the potential mechanisms of TCM for the treatment ...
Biomaterials and engineered microenvironments to control YAP/TAZ-dependent cell behaviour. Nat. Mater. 17, 1063–1075 (2018). Article ADS CAS PubMed PubMed Central Google Scholar Trepat, X. et al. Universal physical responses to stretch in the living cell. Nature 447, 592–59 (2007). ...