cAMPAdenylate cyclase VIEndothelialTransforming growth factor-β (TGFβ1) is a proangiogenic factor both, in vitro and in vivo, that is mainly involved in the later phases of angiogenesis. In an attempt to identify genes that participate in this effect, we found that TGFβ1 down-regulates ...
TGF-beta1-mediated phosphorylation of cAMP response element-binding protein was completely reversed by H-89 (3 microM), a specific inhibitor of PKA. ... Wang,L. - 《Journal of Biological Chemistry》 被引量: 113发表: 1998年 Inhibition of the expression of TGF-β1 and CTGF in human mesangi...
Moreover, TGF-beta1 enhanced phosphorylation of the Aplysia transcriptional activator cAMP response element binding protein (CREB)1, a homologue to vertebrate CREB. Both the TGF-beta1-induced long-term changes in neuronal excitability and the phosphorylation of CREB1 were blocked in the presence of ...
Transforming growth factor β (TGFβ) is a multifunctional cytokine with effects on many cell types. We recently showed that in addition to epithelial barrier enhancing properties, TGFβ causes diminished cAMP-driven chloride secretion in colonic epithelia, in a manner that is p38 MAPK-dependent. ...
TGF-B (transforming growth factor-beta) is a family of multifunctional proteins. TGF-B was originally identified for its ability to induce the growth of normal rodent fibroblast in soft agar. It is now known that TGF-B is a potent growth inhibitor of many normal and transformed cell lines....
序列 重组人转化生长因子-β1蛋白产品,又称Transforming Growth Factor-β1, Differentiation inhibiting factor, Cartilage-inducing factor.其对应NCBI基因号为7042,NCBI基因别称为TGFB2;该基因种属来源为人源,对应Accession号为P61812.该蛋白产品又称Human TGF-beta1, TGF-beta1, TGF beta1, TGFbeta1, h-TGF-bet...
Transcriptional Regulation of the Gene Encoding the Star Protein in the Human Adrenocortical Cell Line, H295R by Camp and Tgfß1 In the present work, we have analyzed the transcriptional regulation of StAR expression in the human adrenocortical cell line H295R. We observed that StAR ... C Br...
Activation of the cAMP-pathway also resulted in Syncytin-1 upregulation, but in contrast to proliferation, classic cell–cell fusions similar to placental syncytiotrophoblasts occurred. Cell–cell fusions were also histologically identified in endometrioid EnCa tumors in vivo. Clonogenic soft agar ...
TGF-beta3, human recombinant 供应商 Biovision 产品货号 4344-5 产品报价 ￥已停产 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868. 产品新闻 背景资料 Transforming growth factor β3 (TGF-β3) is a member of a superfamily of homologo...
This study was to investigate the interplay of cAMP/protein kinase A (PKA) and phosphatidylinositol-3-kinase (PI3K) signaling including mammalian target of rapamycin (mTOR)C1 dependence in FSH- and TGF{szligbeta}1-stimulated steroidogenesis in rat granulosa cells. To achieve this aim, inhibitors ...