Non-Smad pathways in TGF-beta signaling. Cell Res. 2009; 19(1):128-139.11. Massagué J. TGFbeta in Cancer. Cell. 2008;134(2):215-230.12. Gryfe R, Kim H, Hsieh ET, et al. Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. N Engl J ...
信号通路11—TGF-β Smad 信号通路11—TGF-βSmad 订阅号APExBIO ▲ TGF-β / Smad信号通路图 一、TGF-β / Smad调节过程 转化生长因子β（Transforming growth factor beta，TGF-β）信号通路参与生物体和胚胎发育的多种细胞过程，包括细胞生长、细胞分化、凋亡、细胞稳态等。尽管TGF-β信号通路调节的细胞过程...
BMP-2 and TGF-beta 1 differentially control expression of type II procollagen and alpha 10 and alpha 11 integrins in mouse chondrocytes 来自 万方 喜欢 0 阅读量: 16 作者:Bougault,Carole,Perrier,Emeline,Gouttenoire,Jerome,Sandell,Linda,Lundgren-Akerlund,Mallein-Gerin,Frederic,Aubert-Foucher,...
信号通路 11—TGF- β Smad 原创2017-07-24 订阅号 APExBIO ▲ TGF-β / Smad 信号通路图 一、TGF- β / Smad调节过程 转化生长因子 β (Transforming growth factor beta,TGF- β)信号通路参与 生物体和胚胎发育的多种细胞过程,包括细胞生长、细胞分化、凋亡、细胞稳态 等。尽管 TGF- β信号通路调节的细胞...
1. Akhurst RJ, Hata A. Targeting the TGFβ signalling pathway in disease. Nat Rev Drug Discov. 2012;11(10):790-811. 2. Lewis KA, et al. Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature. 2000;404(6776):411-414. ...
(2000). 11 Detection of TGFβ Type II Receptor Hotspot Mutations: The BAT-RII Assay . In: Howe, P.H. (eds) Transforming Growth Factor-Beta Protocols. Methods in Molecular Biology™, vol 142. Humana Press. https://doi.org/10.1385/1-59259-053-5:133 Download citation .RIS .ENW .BIB...
我们的研究表明升高水平的活性TGF-β作为诱导剂和异位骨形成的促进剂,TGF-β可能是HO的治疗靶点。 参考文献: 1 Wang X, Li F, Xie L et al. Inhibition of overactive TGF-beta attenuates progression of heterotopic ossification in mice.Nat Commun2018; 9:551....
1. Akhurst RJ, Hata A. Targeting the TGFβ signalling pathway in disease. Nat Rev Drug Discov. 2012;11(10):790-811. 2. Lewis KA, et al. Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature. 2000;404(6776):411-414. ...
For full engulfment of these cells, binding to integrin alpha(v)beta(3), mediated by the bridging protein, milk fat globule epidermal growth factor-... M Miksa,R Wu,W Dong,... - 《Shock》 被引量: 170发表: 2006年 Yamaguchi, H. et al. Milk fat globule EGF factor 8 in the serum ...
TeicherB.A.(2001).Malignantcells,directorsofthemalignantprocess:Roleoftransforming:Roleoftransforminggrowthfactor-beta(恶性细胞、恶性过程的指标:转化的作用:转化生长因子β的作用).CancerandMetastasisReviews20,133-143. 发明内容 为便于本文的理解,指出:术语“肽p144”指抑制TGF-β1的肽,其特征在于其氨基酸序列...