alpha-Tocopherol also inhibited maternal endotoxemiainduced changes in TGF-beta 1/NOX2/MMP-2 signaling. UUO led to increased collagen deposition in the contralateral kidneys of LPS offspring, which was correlated to increased NADPH oxidase activity and prevented by NADPH oxidase inhibition. In summary...
Anaplastic lymphoma kinase 5 (ALK5; TGFBR1); membrane type 1 matrix metalloproteinase (MT1-MMP; MMP14); small mothers against decapentaplegic homolog 3 (SMAD3); prostaglandin E2 receptor (PGE2, PTGER2); transforming growth factor-|[beta]|1 (TGF-|[beta]|1)...
The migration process is mediated by MMP-2 and NF-kappaB pathway is involved in TGF-beta1-mediated MMP-2 release.Wang YTang ZXue RSingh GKLv YShi KCai KDeng LYang LConnective tissue researchWang, Y.; Tang, Z.; Xue, R.; Singh, G.K.; Lv, Y.; Shi, K.; Cai, K.; Deng, L...
The expression and clinical significance of TGF-beta1 and MMP2 in human renal clear cell carcinoma. Int J Surg Pathol. 2010;18:85-93.Yang SD,Sun RC,Mu HJ,et al. The expression and clinical signifi⁃ cance of TGF-beta1 and MMP2 in human renal clear cell carcinoma[J]. Int J Surg...
Inverse regulation of MMP-2 and MMP-9 by TGF-beta1 in equine chondrocytesThompsonCleggCarterJohn Wiley & Sons, Ltd.International Journal of Experimental Pathology
MMP-2placenta accretatransforming growth factor-&9461ObjectivesEl-Hussieny, MaramMohammed, Enas MostafaZenhom, Nagwa MohamedRefaie, Marwa MonierOkasha, Ahmed MohamedAbd El Tawab, ManalMenia Univ Fac Med Pathol El Minia EgyptFetal and pediatric pathology...
MMP2TGF beta 1/Smad signalling pathwayBackground: A high-fat diet is a major risk factor for coronary heart diseases. Matrix metalloprotease (MMP) expression is changed in many cardiovascular diseases. Selenium, which is an important trace element in animals, has a close relationship with ...
TGF-beta1許多證據顯示人類單核球細胞(THP-1)和巨噬細胞可以分泌合成出結構類似且含有Zinc)金屬離子之內生性蛋白水解酵素.這群水解酵素稱之為基質金屬蛋白酵素(matrix metalloproteinases,MMPs),他們具有可以分解及破壞細胞外基質(extracellular matrix,ECM)之能力,這會導致大部分的ECM沉積.而過多的ECM沉積,通常是發炎...
Effect of hypoxia on stimulatory effect of TGF-beta 1 on MMP-2 and MMP-9 activities in mouse fibroblasts. J Soc Gynecol Investig 2000;7:348-54.Saed GM,Zhang W,Diamond MP.Effect of hypoxia on stimulatory effect of TGF-beta 1 on MMP-2 and MMP-9 activities in mouse fibroblasts. Journal...
Differences in pancreatic immu- nohistochemical staining profiles of TGF-b1, MMP2, and TIMP-2 between autoimmune and alcoholic chronic pancreatitis. Pancreas. 2009;38(7):739-745.CHOI E K,KIM M H,JANG S J,et al.Differences inpancreatic immunohistochemical staining profiles ofTGF-beta1,MMP-2...