The tuned parameters that were used for the random forest model were 800 estimators, Gini impurity criterion, minimum of 2 samples at a leaf node, minimum of 2 samples to split an internal node, and a maximum depth of 10. For the random forest classifier, important features contributing to ...
T-cell receptor (TCR) gene rearrangement clonality studies help resolve atypical T-cell proliferations in the context of suspected malignancy. However, the interpretation criteria for this assay using a next-generation sequencing (NGS) platform have not been extensively explored and standardized. Thus,...
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To test whether GDF-15 impairs activation of Lymphocyte function-associated antigen (LFA)−1 on human T cells (similar to a previously described effect on murine myeloid cells28), we ran stimulated T cells over a layer of immobilized intercellular adhesion molecule (ICAM)−1. Adhesion was ef...
than 2% of the total cells in at least three normal tissues as a potentially risky gene (PRG) [117]. By employing this criterion, they identified PRGs neglected by bulk expression analysis, such as EGFR, PSCA and KDR (VEGFR2), and suggested that close surveillance was needed for early ...
s test: Unadjusted 2-sidedpvalues <0.05 are indicated. VZV varicella-zoster virus, HZ herpes zoster rash, Con contralateral, D45 day 45, D90 day 90, D360 day 360, D500 day 500, ORF open-reading frame, HLA human leukocyte antigen, TCL T cell line. Source data are provided as a ...
If required, raw nd2 format image stacks were deconvoluted using Huygens using a theoretical point spread function classical maximum likelihood estimation using 100 iterations and a quality stop criterion of 0.05. Immunofluorescent staining of immune synapse components of REP T cell/T2 cell conjugates ...
The best model was selected as having the smallest AIC (Akaike Information Criterion), an estimator of prediction error (Table 4). The forest plot as well as other graphical presentations were constructed with Stata version 17, while statistical analyses including the mixed models were performed ...
The CTL activity of splenocytes from mice treated with RdB/IL-12, RdB/IL-18 or RdB/IL-12/IL-18 was specific to a given tumor, as no CTL activity could be detected when NIH3T3 cells were used as target cells. These results show that RdB/IL-12/IL-18-treated mice had a higher ...
Prolongation of electrical systole (Q-T interval) as added criterion in the levy anoxia test Author links open overlay panelD.C. Roehm M.D. ∗, R.C. Kory M.D., G.R. Meneely M.D.Show more Add to Mendeley Share Cite https://doi.org/10.1016/0002-9343(53)90298-8Get rights and ...