Adriani W, Laviola G (2000) A unique hormonal and behavioral hyporesponsivity to both forced novelty and d-amphetamine in periadolescent mice. Neuropharmacol 39:334–346 CAS Google Scholar Adriani W, Macri S, Pacifici R, Laviola G (2002) Peculiar vulnerability to nicotine oral self-administ...
Here, we investigate the neurobiological basis of stress resilience, by showing that neural responsitivity of the noradrenergic locus coeruleus (LC-NE) and associated pupil responses are related to the subsequent change in measures of anxiety and depression in response to prolonged real-life stress....
However, under the condition of pre-implantation of melatonin, the adverse effects of HS on the sperm quality of dairy goats were partially alleviated throughout the entire experimental period (Fig. 1C, D, E). Sperm quality analysis revealed a significantly higher sperm malformation (P < ...
近4个月来时有腹胀，大便带粘液，大便次数增加，每日2~3次，无排便不尽及里急后重感。体检：T36度，p90次/分，BP115／70mmHg，腹膨隆,未见肠型，腹软，右下腹可触及一斜行肿块，质韧压痛，腹部透视见一气液平面。WBC9×10⁹／L，中性粒细胞比例0.75，发病以来患者体重减轻5千克，睡眠欠佳。
Lysergic acid diethylamide (LSD) is a serotonergic psychedelic compound receiving increasing interest due to putative anxiolytic and antidepressant properties. However, the potential neurobiological mechanisms mediating these effects remain elusive. Empl
It can be concluded that, a stressed nurse is a dangerous nurse, especially, when stress causes nurses’ cognitive impairment, hence leading them to make grave medical errors. WRS can also spill into nurses’ personal lives causing poor social life outside the workplace including strained ...
(Schnall et al., 2009). The notion of a fit or misfit between extrinsic demands and the working person’s resources of coping with these demands has been elaborated in more recent extensions of the original model (Bakker and Demerouti, 2007), but the empirical evidence of these extensions...
from which 20 % of the samples were randomly set aside before all preprocessing steps, exhibits very similar performance metrics to the model trained on all samples (Table S3). The performance of the independent hold-out datasets imply a high degree of similarity and demonstrate a high predicti...
The immunoblot analyses to detect RsbR1, RsbS and RsbT in the subcellular fractions were carried out using affinity-purified antibodies. An important control included in these experiments was a polar ΔrsbR1mutant known to have affected the expression of the downstream genesrsbSandrsbT30. These ...
Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease that affects an estimated 300 million people worldwide, but its pathogenesis is poorly understood. The heritability estimate of MDD is 30–40%, suggesting that gene