The various categories of experimental autoimmune disease in laboratory rodents are briefly described here, and the rationale that was used in the selection of suitable experimental autoimmune diseases for translational research is explained. The two models that provided the bulk of the data needed for...
"We accept that patients in the transplant arm have a higher risk of dying upfront of complications from the transplant but that their survival in the long run will be better than control patients," explained Dr. van Laar, who is professor of clinical rheumatology at the Newcastle University ...
and individual patients were also represented with multiple samples in this analysis (Supplementary Table3). It may also reflect the heterogeneity of alloHSCT patient journeys and the significant effects of these on the microbiome33. Consistently, the enriched...
Objective To observer the clinical effects of cord blood stem cell transplantation combined with traditional Chinese therapy for kidney nourishing and dampness elimination in treatment of patients with child A or B grade liver cirrhosis,and related mechanism. Methods 50 patients with child A or B grad...
as described in a previous study22. The meta-regression was univariate rather than multivariate and we calculated adjusted R2values to explain the proportion of the observed variability in the observed effect size for a group of experiments explained by variation in the independent variable in questio...
The strong correlation between high-risk karyotype and unfavorable outcome in our study could be explained in part by the fact that the most common new drug incorporated in salvage therapies was thalidomide (52% in the donor group, 39% in the no-donor group), which has shown less-convincing...
This can be explained by the limited number of patients, the variable quality of the isolated hepatocytes, and the different protocols used between care centers. Moreover, current culture conditions fail to efficiently expand primary hepatocytes in vitro to a sufficient scale for the treatment of ...
The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell population of multipotential stem/progenitor cells commonly referred to as mesenchymal stem cells, multipotential stromal cells, mesenchymal stromal cells, and mesench
The seemingly paradoxical discovery—that a mutation detrimental in non-transplant patientswith CH can be beneficial in transplant recipients—may be explained by DNMT3A's role within cells. In otherwise healthy people, DNMT3A mutations are associated with increased immune system activity and inflammation...
(HealthDay)—A stem cell transplant may help some people with multiple sclerosis (MS) when standard drugs fail, a new clinical trial finds.