Stem Cell Therapy for MS Shows Promise More By Dennis ThompsonHealthDay Reporter HealthDay MONDAY, Dec. 29, 2014 (HealthDay News) -- An experimental therapy that kills off and then "resets" the immune system has given three years of remission to a small group of multiple sclerosis patients,...
For patients with multiple sclerosis (MS), current treatment options only address early-stage symptoms of the debilitating disease. Now, new research has found a potential treatment that could both stop disease progression and repair existing damage.Nicole Kwan...
The researchers hope that a cell transplant shortly after the injury will limit that over-response while still promoting anti-inflammatory healing. The Houston trial has enrolled about 14 of the 55 patients it needs for its adult trial and about 38 of 50 patients for a pediatric trial. (You ...
Is HSC therapy for MS safe?Early transplant-related complications, like fever, diarrhea, and low blood cell counts, are common after the aHSCT procedure.More rarely, serious complications may occur. For example, because aHSCT involves wiping out the immune system, patients undergoing the procedure...
Better pre-transplant treatment options forTP53-mutated MDS: cytoreductive or non-cytoreductive therapy? Bingqian Jiang Tingting Yang Jimin Shi Research04 Dec 2024Bone Marrow Transplantation P: 1-9 High-dose chemotherapy with autologous haematopoietic stem cell transplantation in patients with isolated vit...
Mesenchymal stem cells (MSCs), the major stem cells for cell therapy, have been used in the clinic for approximately 10 years. From animal models to clinical trials, MSCs have afforded promise in the treatment of numerous diseases, mainly tissue injury and immune disorders. In this review, we...
No effective blood-flow enhancement therapies are available for patients with severe peripheral arterial disease (SPAD), thus amputation remains the only option for relief of rest pain or gangrene. Autologous bone marrow-derived stem cell therapy (ABMSCT) is an emerging modality to induce angiogenesi...
Now, the patients are likely to remain blind, said co-author Thomas Albini, an associate professor of clinical ophthalmology at the University of Miami, where two of the patients were treated for complications from the stem cell treatments. ...
MSC-Exos for graft-versus-host disease (GvHD) Allogeneic hematopoietic stem cell transplantation (HSCT) is a potential life-saving procedure to treat patients with hematologic malignancies. One of the most severe complications associated with HSCT is acute or chronic graft-versus-host disease (GvHD)...
In an analysis of a small group of the participants using advanced magnetic imaging, we noted an association between higher stem cell doses and a reduction in brain volume. Similar effects have been seen with potentdrugs used for patients with early MS, suggesting a possible role of the cells...